Values CatLog read from this paper
Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity
PMID 30744994doi:10.1016/j.str.2019.01.004Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (12 values) from this paper: DNA gyrase from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| DNA gyrase | Mycobacterium tuberculosis | adenosine 5'-triphosphate | 0.05 | 0.7 | 0.071 calc. | pH 7.5, 30 °C | Open record: DNA gyrase, adenosine 5'-triphosphate |
| DNA gyrase | Mycobacterium tuberculosis | adenosine 5'-triphosphate | 0.06 | 0.8 | 0.075 calc. | pH 7.5, 30 °C | Open record: DNA gyrase, adenosine 5'-triphosphate |
| DNA gyrasevariant D211K/E212K/E213K/E214K (GyrA 211DEEE214 to 211KKKK214; GyrBAKKKK) | Mycobacterium tuberculosis | adenosine 5'-triphosphate | 0.09 | 1 | 0.090 calc. | pH 7.5, 30 °C | Open record: DNA gyrase variant D211K/E212K/E213K/E214K (GyrA 211DEEE214 to 211KKKK214; GyrBAKKKK), adenosine 5'-triphosphate |
| DNA gyrasevariant E221K/D225K/E228K/R236E/H244A (GyrB; GyrBAmC-loop) | Mycobacterium tuberculosis | adenosine 5'-triphosphate | 0.08 | 0.7 | 0.11 calc. | pH 7.5, 30 °C | Open record: DNA gyrase variant E221K/D225K/E228K/R236E/H244A (GyrB; GyrBAmC-loop), adenosine 5'-triphosphate |
| DNA gyraseΔC-loop (GyrB residues 214-245 deleted; GyrBA57ΔC-loop) | Mycobacterium tuberculosis | adenosine 5'-triphosphate | 0.06 | 0.75 | 0.080 calc. | pH 7.5, 30 °C | Open record: DNA gyrase ΔC-loop (GyrB residues 214-245 deleted; GyrBA57ΔC-loop), adenosine 5'-triphosphate |
| DNA gyraseΔC-loop (GyrB residues 214-245 deleted; GyrBAΔC-loop) | Mycobacterium tuberculosis | adenosine 5'-triphosphate | 0.11 | 0.3 | 0.37 calc. | pH 7.5, 30 °C | Open record: DNA gyrase ΔC-loop (GyrB residues 214-245 deleted; GyrBAΔC-loop), adenosine 5'-triphosphate |