Values CatLog read from this paper
Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis
PMID 31548418doi:10.1073/pnas.1908770116Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (15 values) from this paper: cis-aconitate decarboxylase (hCAD), cis-aconitate decarboxylase (aCAD), cis-aconitate decarboxylase (mCAD) from Homo sapiens, Aspergillus terreus, Mus musculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cis-aconitate decarboxylase (aCAD) | Aspergillus terreus | cis-aconitate | 18.4 | 9 | 2 | pH 6.5, 37 °C | Open record: cis-aconitate decarboxylase (aCAD), cis-aconitate |
| cis-aconitate decarboxylase (hCAD) | Homo sapiens | cis-aconitate | 0.94 | 0.61 | 1.6 | pH 6.5, 37 °C | Open record: cis-aconitate decarboxylase (hCAD), cis-aconitate |
| cis-aconitate decarboxylase (hCAD)variant N152S | Homo sapiens | cis-aconitate | 1.45 | 0.58 | 2.5 | pH 6.5, 37 °C | Open record: cis-aconitate decarboxylase (hCAD) variant N152S, cis-aconitate |
| cis-aconitate decarboxylase (hCAD)variant R273H | Homo sapiens | cis-aconitate | 1.1 | 0.34 | 3.2 | pH 6.5, 37 °C | Open record: cis-aconitate decarboxylase (hCAD) variant R273H, cis-aconitate |
| cis-aconitate decarboxylase (mCAD) | Mus musculus | cis-aconitate | 4.94 | 0.65 | 7.6 | pH 6.5, 37 °C | Open record: cis-aconitate decarboxylase (mCAD), cis-aconitate |