EC 4.1.1.6: cis-aconitate decarboxylase
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CatLog read 40 records for EC 4.1.1.6 from 2 papers, for 3 organisms. Names in these papers: hACOD1 (human cis-aconitate decarboxylase ACOD1), mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate decarboxylase ACOD1 (hACOD1), aCAD (Aspergillus terreus cis-aconitate decarboxylase) and 3 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 1 record for EC 4.1.1.6 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.1.1.6 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Effect of pH and buffer on substrate binding and catalysis by cis-aconitate decarboxylase | Aspergillus terreus, Homo sapiens and 1 more | 35 |
| Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis | Aspergillus terreus, Homo sapiens and 1 more | 5 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| aCAD (Aspergillus terreus cis-aconitate decarboxylase) | Aspergillus terreus | cis-aconitate | 0.38 | 0.41 | 0.935 | pH 5.5, 37 °C | PMID 39934230 | Open record: aCAD (Aspergillus terreus cis-aconitate decarboxylase), cis-aconitate |
| aCAD (Aspergillus terreus cis-aconitate decarboxylase) | Aspergillus terreus | cis-aconitate | 1.31 | 0.16 | 7.947 | pH 6, 37 °C | PMID 39934230 | Open record: aCAD (Aspergillus terreus cis-aconitate decarboxylase), cis-aconitate |
| aCAD (Aspergillus terreus cis-aconitate decarboxylase) | Aspergillus terreus | cis-aconitate | 2.6 | 0.47 | 0.594 | pH 6.5, 37 °C | PMID 39934230 | Open record: aCAD (Aspergillus terreus cis-aconitate decarboxylase), cis-aconitate |
| aCAD (Aspergillus terreus cis-aconitate decarboxylase) | Aspergillus terreus | cis-aconitate | 2.8 | 2.1 | 1.306 | pH 7, 37 °C | PMID 39934230 | Open record: aCAD (Aspergillus terreus cis-aconitate decarboxylase), cis-aconitate |
| aCAD (Aspergillus terreus cis-aconitate decarboxylase) | Aspergillus terreus | cis-aconitate | 2 | 20 | 0.101 | pH 7.5, 37 °C | PMID 39934230 | Open record: aCAD (Aspergillus terreus cis-aconitate decarboxylase), cis-aconitate |
| cis-aconitate decarboxylase (aCAD) | Aspergillus terreus | cis-aconitate | 18.4 | 9 | 2 | pH 6.5, 37 °C | PMID 31548418 | Open record: cis-aconitate decarboxylase (aCAD), cis-aconitate |
| cis-aconitate decarboxylase (hCAD) | Homo sapiens | cis-aconitate | 0.94 | 0.61 | 1.6 | pH 6.5, 37 °C | PMID 31548418 | Open record: cis-aconitate decarboxylase (hCAD), cis-aconitate |
| cis-aconitate decarboxylase (hCAD)variant N152S | Homo sapiens | cis-aconitate | 1.45 | 0.58 | 2.5 | pH 6.5, 37 °C | PMID 31548418 | Open record: cis-aconitate decarboxylase (hCAD) variant N152S, cis-aconitate |
| cis-aconitate decarboxylase (hCAD)variant R273H | Homo sapiens | cis-aconitate | 1.1 | 0.34 | 3.2 | pH 6.5, 37 °C | PMID 31548418 | Open record: cis-aconitate decarboxylase (hCAD) variant R273H, cis-aconitate |
| cis-aconitate decarboxylase (mCAD) | Mus musculus | cis-aconitate | 4.94 | 0.65 | 7.6 | pH 6.5, 37 °C | PMID 31548418 | Open record: cis-aconitate decarboxylase (mCAD), cis-aconitate |
| cis-aconitate decarboxylase ACOD1 (hACOD1)variant H159A (His159Ala) | Homo sapiens | cis-aconitate | 0.147 | 0.23 | 0.639 | pH 5.5, 37 °C | PMID 39934230 | Open record: cis-aconitate decarboxylase ACOD1 (hACOD1) variant H159A (His159Ala), cis-aconitate |
| cis-aconitate decarboxylase ACOD1 (hACOD1)variant H159A (His159Ala) | Homo sapiens | cis-aconitate | 0.13 | 0.105 | 1.238 | pH 6, 37 °C | PMID 39934230 | Open record: cis-aconitate decarboxylase ACOD1 (hACOD1) variant H159A (His159Ala), cis-aconitate |
| cis-aconitate decarboxylase ACOD1 (hACOD1)variant H159A (His159Ala) | Homo sapiens | cis-aconitate | 0.133 | 0.155 | 0.858 | pH 6.5, 37 °C | PMID 39934230 | Open record: cis-aconitate decarboxylase ACOD1 (hACOD1) variant H159A (His159Ala), cis-aconitate |
| cis-aconitate decarboxylase ACOD1 (hACOD1)variant H159A (His159Ala) | Homo sapiens | cis-aconitate | 0.133 | 0.43 | 0.309 | pH 7, 37 °C | PMID 39934230 | Open record: cis-aconitate decarboxylase ACOD1 (hACOD1) variant H159A (His159Ala), cis-aconitate |
| cis-aconitate decarboxylase ACOD1 (hACOD1)variant H159A (His159Ala) | Homo sapiens | cis-aconitate | 0.118 | 1.65 | 0.072 | pH 7.5, 37 °C | PMID 39934230 | Open record: cis-aconitate decarboxylase ACOD1 (hACOD1) variant H159A (His159Ala), cis-aconitate |
| cis-aconitate decarboxylase ACOD1 (hACOD1)variant H159A (His159Ala) | Homo sapiens | cis-aconitate | 0.13 | 7 | 0.019 | pH 7.75, 37 °C | PMID 39934230 | Open record: cis-aconitate decarboxylase ACOD1 (hACOD1) variant H159A (His159Ala), cis-aconitate |
| cis-aconitate decarboxylase ACOD1 (hACOD1)variant H159A (His159Ala) | Homo sapiens | cis-aconitate | 0.21 | 30 | 0.0070 calc. | pH 8, 37 °C | PMID 39934230 | Open record: cis-aconitate decarboxylase ACOD1 (hACOD1) variant H159A (His159Ala), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 0.7 | 0.4 | 1.751 | pH 5.5, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 0.91 | 0.29 | 3.197 | pH 6, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 0.93 | 0.17 | 5.525 | pH 6.5, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 0.94 | 0.23 | 4.06 | pH 7, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 0.9 | 0.47 | 1.933 | pH 7.5, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 1.02 | 2.6 | 0.392 | pH 7.75, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 1.02 | 4.7 | 0.217 | pH 8, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1) | Homo sapiens | cis-aconitate | 2.3 | 33 | 0.071 | pH 8.25, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1), cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1)variant H159A | Homo sapiens | cis-aconitate | 0.147 | 0.23 | 0.639 | pH 5.5, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1) variant H159A, cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1)variant H159A | Homo sapiens | cis-aconitate | 0.13 | 0.105 | 1.238 | pH 6, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1) variant H159A, cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1)variant H159A | Homo sapiens | cis-aconitate | 0.133 | 0.155 | 0.858 | pH 6.5, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1) variant H159A, cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1)variant H159A | Homo sapiens | cis-aconitate | 0.133 | 0.43 | 0.309 | pH 7, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1) variant H159A, cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1)variant H159A | Homo sapiens | cis-aconitate | 0.118 | 1.65 | 0.072 | pH 7.5, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1) variant H159A, cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1)variant H159A | Homo sapiens | cis-aconitate | 0.13 | 7 | 0.019 | pH 7.75, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1) variant H159A, cis-aconitate |
| hACOD1 (human cis-aconitate decarboxylase ACOD1)variant H159A | Homo sapiens | cis-aconitate | 0.21 | 30 | 0.0070 calc. | pH 8, 37 °C | PMID 39934230 | Open record: hACOD1 (human cis-aconitate decarboxylase ACOD1) variant H159A, cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 3.6 | 2.1 | 1.714 | pH 5.5, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 4 | 0.082 | 48.54 | pH 6, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 6.2 | 0.072 | 85.50 | pH 6.5, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 8 | 0.17 | 47.5 | pH 7, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 9.1 | 0.64 | 14.07 | pH 7.5, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 8.7 | 1.82 | 4.792 | pH 7.75, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 12 | 6.5 | 1.769 | pH 8, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |
| mACOD1 (mouse cis-aconitate decarboxylase ACOD1) | Mus musculus | cis-aconitate | 21 | 28 | 0.728 | pH 8.25, 37 °C | PMID 39934230 | Open record: mACOD1 (mouse cis-aconitate decarboxylase ACOD1), cis-aconitate |