Values CatLog read from this paper
Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
PMID 19351325doi:10.1042/bj20090336Open in Browse
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CatLog read 14 records (42 values) from this paper: citramalate synthase (LiCMS) from Leptospira interrogans.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| citramalate synthase (LiCMS) | Leptospira interrogans | acetyl coenzyme A20 µM isoleucine (feedback inhibitor) | 10.6 | 2.272 | 4.6 | pH 7.7 | Open record: citramalate synthase (LiCMS), acetyl coenzyme A |
| citramalate synthase (LiCMS) | Leptospira interrogans | acetyl coenzyme A60 µM isoleucine (feedback inhibitor) | 11.1 | 4.246 | 2.6 | pH 7.7 | Open record: citramalate synthase (LiCMS), acetyl coenzyme A |
| citramalate synthase (LiCMS) | Leptospira interrogans | pyruvate1 µM isoleucine (feedback inhibitor) | 9.2 | 0.094 | 98 | pH 7.7 | Open record: citramalate synthase (LiCMS), pyruvate |
| citramalate synthase (LiCMS) | Leptospira interrogans | pyruvate4 µM isoleucine (feedback inhibitor) | 9.3 | 0.178 | 52 | pH 7.7 | Open record: citramalate synthase (LiCMS), pyruvate |
| citramalate synthase (LiCMS)variant D431A | Leptospira interrogans | acetyl coenzyme A | 2 | 0.629 | 3.2 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant D431A, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant H400A/H408A | Leptospira interrogans | acetyl coenzyme A | 9.1 | 1.554 | 5.9 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant H400A/H408A, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant I458A | Leptospira interrogans | acetyl coenzyme A | 0.7 | 0.838 | 0.8 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant I458A, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant L451V | Leptospira interrogans | acetyl coenzyme A | 2.4 | 1.711 | 1.4 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant L451V, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant P493A | Leptospira interrogans | acetyl coenzyme A | 4 | 0.743 | 5.4 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant P493A, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant Q495A | Leptospira interrogans | acetyl coenzyme A | 3.7 | 0.712 | 5.2 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant Q495A, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant T464A | Leptospira interrogans | acetyl coenzyme A | 2.4 | 0.626 | 3.8 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant T464A, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant V468A | Leptospira interrogans | acetyl coenzyme A | 5 | 1.116 | 4.5 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant V468A, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant Y430L | Leptospira interrogans | acetyl coenzyme A | 4.5 | 1.097 | 4.1 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant Y430L, acetyl coenzyme A |
| citramalate synthase (LiCMS)variant Y454A | Leptospira interrogans | acetyl coenzyme A | 0.6 | 0.803 | 0.74 | pH 7.7 | Open record: citramalate synthase (LiCMS) variant Y454A, acetyl coenzyme A |