Values CatLog read from this paper
Kinetic properties and specificity of trimeric Plasmodium falciparum and human dUTPases
PMID 19879316doi:10.1016/j.biochi.2009.10.008Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 17 records (33 values) from this paper: dUTPase (PfdUTPase), dUTPase (hdUTPase) from Plasmodium falciparum, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 2 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dUTPase (hdUTPase) | Homo sapiens | 2'-deoxycytidine 5'-triphosphate | — | 0.687 | 0.1616 | pH 7, 25 °C | Open record: dUTPase (hdUTPase), 2'-deoxycytidine 5'-triphosphate |
| dUTPase (hdUTPase) | Homo sapiens | 2'-deoxyuridine 5'-triphosphate | — | 0.0011 | 6.6 × 10³ | pH 7, 25 °C | Open record: dUTPase (hdUTPase), 2'-deoxyuridine 5'-triphosphate |
| dUTPase (hdUTPase) | Homo sapiens | 5-fluoro-2'-deoxyuridine 5'-triphosphate | — | 0.0061 | 600 | pH 7, 25 °C | Open record: dUTPase (hdUTPase), 5-fluoro-2'-deoxyuridine 5'-triphosphate |
| dUTPase (hdUTPase) | Homo sapiens | 5-fluoro-2'-deoxyuridine 5'-triphosphate | 3.2 | 0.0042 | 760 calc. | 25 °C | Open record: dUTPase (hdUTPase), 5-fluoro-2'-deoxyuridine 5'-triphosphate |
| dUTPase (hdUTPase) | Homo sapiens | 5-iodo-2'-deoxyuridine 5'-triphosphate | — | 0.523 | 0.0061 | pH 7, 25 °C | Open record: dUTPase (hdUTPase), 5-iodo-2'-deoxyuridine 5'-triphosphate |
| dUTPase (hdUTPase) | Homo sapiens | thymidine 5'-triphosphate | — | 0.761 | 0.01971 | pH 7, 25 °C | Open record: dUTPase (hdUTPase), thymidine 5'-triphosphate |
| dUTPase (hdUTPase) | Homo sapiens | uridine 5'-triphosphate | — | 0.54 | 0.01278 | pH 7, 25 °C | Open record: dUTPase (hdUTPase), uridine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 2'-deoxyadenosine 5'-triphosphate | — | 1.13 | 0.00265 | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), 2'-deoxyadenosine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 2'-deoxycytidine 5'-triphosphate | — | 0.465 | 0.02172 | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), 2'-deoxycytidine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 2'-deoxyguanosine 5'-triphosphate | — | 1.96 | 1.3 × 10⁻⁴ | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), 2'-deoxyguanosine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 2'-deoxyuridine 5'-triphosphate | — | 0.00187 | 7.1 × 10³ | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), 2'-deoxyuridine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 5-fluoro-2'-deoxyuridine 5'-triphosphate | — | 0.00173 | 110 | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), 5-fluoro-2'-deoxyuridine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 5-fluoro-2'-deoxyuridine 5'-triphosphate | 4 | 0.0031 | 1.3 × 10³ calc. | 25 °C | Open record: dUTPase (PfdUTPase), 5-fluoro-2'-deoxyuridine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 5-iodo-2'-deoxyuridine 5'-triphosphate | — | 0.438 | 0.00525 | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), 5-iodo-2'-deoxyuridine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | 5-iodo-2'-deoxyuridine 5'-triphosphatekcat per active site | 0.002 | — | — | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), 5-iodo-2'-deoxyuridine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | thymidine 5'-triphosphate | — | 0.29 | 0.0092 | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), thymidine 5'-triphosphate |
| dUTPase (PfdUTPase) | Plasmodium falciparum | uridine 5'-triphosphate | — | 0.571 | 0.01121 | pH 7, 25 °C | Open record: dUTPase (PfdUTPase), uridine 5'-triphosphate |