CatLogenzyme kinetics catalog

Values CatLog read from this paper

Importance of the prime subsites of the C1s protease of the classical complement pathway for recognition of substrates

PMID 14674770doi:10.1021/bi035507bOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 44 records (48 values) from this paper: C1s (complement C1s protease) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.21.42

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Ala-Glu-Ile-Lys(Dnp)-NH21.69 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Gln-Glu-Ile-Lys(Dnp)-NH21.83 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Glu-Glu-Ile-Lys(Dnp)-NH24.21 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-His-Glu-Ile-Lys(Dnp)-NH23.23 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Ala-Ile-Lys(Dnp)-NH20.00274——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Gln-Ile-Lys(Dnp)-NH20.00232——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Ala-Lys(Dnp)-NH23.92 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Gln-Lys(Dnp)-NH29.78 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Glu-Lys(Dnp)-NH29.78 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-His-Lys(Dnp)-NH22.44 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Ile-Lys(Dnp)-NH2commercial (Calbiochem); activated two-chain human C1s2.1 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Ile-Lys(Dnp)-NH2+0.15 mM CaCl2; commercial (Calbiochem)8.31 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Ile-Lys(Dnp)-NH2+0.15 mM CaCl2; spontaneously activated 30 min at 37 °C0.00178——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Leu-Lys(Dnp)-NH29.78 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Lys(Dnp)-NH23.19 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Lys-Lys(Dnp)-NH28.67 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Met-Lys(Dnp)-NH21.71 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Phe-Lys(Dnp)-NH22.2 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Pro-Lys(Dnp)-NH28.07 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Thr-Lys(Dnp)-NH24.4 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-His-Ile-Lys(Dnp)-NH20.00821——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Leu-Ile-Lys(Dnp)-NH20.00296——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Lys(Dnp)-NH26.83 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Lys-Ile-Lys(Dnp)-NH21.36 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Met-Ile-Lys(Dnp)-NH20.00227——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Phe-Ile-Lys(Dnp)-NH20.00288——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Pro-Ile-Lys(Dnp)-NH20.00244——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Leu-Thr-Ile-Lys(Dnp)-NH20.00279——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Lys(Dnp)-NH23.94 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Met-Glu-Ile-Lys(Dnp)-NH21.19 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Phe-Glu-Ile-Lys(Dnp)-NH23.3 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Pro-Glu-Ile-Lys(Dnp)-NH21.89 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Ala-Thr-Glu-Ile-Lys(Dnp)-NH21.47 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Gln-Leu-Glu-Ile-Lys(Dnp)-NH27.02 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Glu-Leu-Glu-Ile-Lys(Dnp)-NH22.05 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-His-Leu-Glu-Ile-Lys(Dnp)-NH24.15 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Leu-Leu-Glu-Ile-Lys(Dnp)-NH27.02 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Lys-Leu-Glu-Ile-Lys(Dnp)-NH27.62 × 10⁻⁵——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Met-Leu-Glu-Ile-Lys(Dnp)-NH22.39 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Phe-Leu-Glu-Ile-Lys(Dnp)-NH21.55 × 10⁻⁴——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Gly-Leu-Gln-Arg-Thr-Leu-Glu-Ile-Lys(Dnp)-NH20.00155——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiens2Abz-Ser-Leu-Gly-Arg-Lys-Ile-Gln-Ile-Lys(Dnp)-NH20.00139——pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiensZ-Gly-Leu-Gln-Arg-AMC0.380.35811.06pH 7.4, 37 °COpen
C1s (complement C1s protease)Homo sapiensZ-Ser-Leu-Gly-Arg-NHMec12.890.136994.2pH 7.4, 37 °COpen