Values CatLog read from this paper
Phosphate sensitivity of KPC-2: a hidden variable in β-lactamase kinetics
PMID 41616264doi:10.1128/aac.01069-25Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 48 records (144 values) from this paper: KPC-2, CTX-M-14, TEM-1.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CTX-M-14 | — | cefotaxime50 mM sodium phosphate (PO4) | 140 | 0.13 | 1 × 10³ | pH 7 | Open record: CTX-M-14, cefotaxime |
| CTX-M-14 | — | cefotaxime10 mM HEPES + 150 mM NaCl | 160 | 0.1 | 2 × 10³ | pH 7 | Open record: CTX-M-14, cefotaxime |
| CTX-M-14 | — | cefotaxime50 mM Tris-HCl | 140 | 0.083 | 2 × 10³ | pH 7 | Open record: CTX-M-14, cefotaxime |
| CTX-M-14 | — | cephalothin10 mM PO4 (sodium phosphate) | 540 | 0.057 | 9 × 10³ | pH 7 | Open record: CTX-M-14, cephalothin |
| CTX-M-14 | — | cephalothin50 mM PO4 (sodium phosphate) | 680 | 0.079 | 9 × 10³ | pH 7 | Open record: CTX-M-14, cephalothin |
| CTX-M-14 | — | cephalothin50 mM PO4 (sodium phosphate) + 0.15 M NaCl | 1.1 × 10³ | 0.11 | 1 × 10⁴ | pH 7 | Open record: CTX-M-14, cephalothin |
| CTX-M-14 | — | cephalothin10 mM HEPES + 0.15 M NaCl | 1.4 × 10³ | 0.15 | 1 × 10⁴ | pH 7 | Open record: CTX-M-14, cephalothin |
| CTX-M-14 | — | cephalothin50 mM Tris-HCl | 830 | 0.056 | 2 × 10⁴ | pH 7 | Open record: CTX-M-14, cephalothin |
| KPC-2 | — | ampicillin10 mM sodium phosphate (PO4) | 160 | 0.14 | 1 × 10³ | pH 7 | Open record: KPC-2, ampicillin |
| KPC-2 | — | ampicillin50 mM sodium phosphate (PO4) | 160 | 0.24 | 700 | pH 7 | Open record: KPC-2, ampicillin |
| KPC-2 | — | ampicillin50 mM sodium phosphate (PO4) + 150 mM NaCl | 170 | 0.29 | 600 | pH 7 | Open record: KPC-2, ampicillin |
| KPC-2 | — | ampicillin10 mM HEPES + 150 mM NaCl | 210 | 0.072 | 3 × 10³ | pH 7 | Open record: KPC-2, ampicillin |
| KPC-2 | — | ampicillin50 mM Tris-HCl | 170 | 0.056 | 3 × 10³ | pH 7 | Open record: KPC-2, ampicillin |
| KPC-2 | — | cephalothin10 mM PO4 (sodium phosphate) | 120 | 0.025 | 5 × 10³ | pH 7 | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin50 mM PO4 (sodium phosphate) | 150 | 0.086 | 2 × 10³ | pH 7 | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin50 mM PO4 (sodium phosphate) + 0.15 M NaCl | 300 | 0.11 | 3 × 10³ | pH 7 | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin10 mM HEPES + 0.15 M NaCl | 390 | 0.027 | 1 × 10⁴ | pH 7 | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin50 mM Tris-HCl | 160 | 0.0055 | 3 × 10⁴ | pH 7 | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin10 mM sodium phosphate | 187 | 0.069 | 2.7 × 10³ | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin10 mM HEPES (sodium salt) | 186 | 0.026 | 7.2 × 10³ | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin25 mM sodium phosphate | 172 | 0.145 | 1.2 × 10³ | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin25 mM HEPES (sodium salt) | 197 | 0.036 | 5.5 × 10³ | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin50 mM sodium phosphate | 159 | 0.198 | 840 | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin50 mM HEPES (sodium salt) | 208 | 0.058 | 3.6 × 10³ | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin75 mM sodium phosphate | 125 | 0.189 | 660 | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin75 mM HEPES (sodium salt) | 245 | 0.079 | 3.1 × 10³ | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin100 mM sodium phosphate | 167 | 0.241 | 690 | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | cephalothin100 mM HEPES (sodium salt) | 272 | 0.081 | 3.4 × 10³ | pH 7, 25 °C | Open record: KPC-2, cephalothin |
| KPC-2 | — | imipenem10 mM sodium phosphate (PO4) | 36 | 0.11 | 300 | pH 7 | Open record: KPC-2, imipenem |
| KPC-2 | — | imipenem50 mM sodium phosphate (PO4) | 39 | 0.29 | 100 | pH 7 | Open record: KPC-2, imipenem |
| KPC-2 | — | imipenem50 mM sodium phosphate (PO4) + 150 mM NaCl | 45 | 0.15 | 300 | pH 7 | Open record: KPC-2, imipenem |
| KPC-2 | — | imipenem10 mM HEPES + 150 mM NaCl | 24 | 0.048 | 500 | pH 7 | Open record: KPC-2, imipenem |
| KPC-2 | — | imipenem50 mM Tris-HCl | 53 | 0.022 | 2 × 10³ | pH 7 | Open record: KPC-2, imipenem |
| KPC-2variant T237G | — | ampicillin10 mM sodium phosphate (PO4) | 210 | 0.068 | 3 × 10³ | pH 7 | Open record: KPC-2 variant T237G, ampicillin |
| KPC-2variant T237G | — | ampicillin50 mM sodium phosphate (PO4) | 240 | 0.097 | 2 × 10³ | pH 7 | Open record: KPC-2 variant T237G, ampicillin |
| KPC-2variant T237G | — | ampicillin50 mM sodium phosphate (PO4) + 150 mM NaCl | 270 | 0.096 | 3 × 10³ | pH 7 | Open record: KPC-2 variant T237G, ampicillin |
| KPC-2variant T237G | — | ampicillin10 mM HEPES + 150 mM NaCl | 390 | 0.18 | 2 × 10³ | pH 7 | Open record: KPC-2 variant T237G, ampicillin |
| KPC-2variant T237G | — | ampicillin50 mM Tris-HCl | 250 | 0.064 | 4 × 10³ | pH 7 | Open record: KPC-2 variant T237G, ampicillin |
| KPC-2variant T237G | — | cephalothin10 mM PO4 (sodium phosphate) | 30 | 0.017 | 2 × 10³ | pH 7 | Open record: KPC-2 variant T237G, cephalothin |
| KPC-2variant T237G | — | cephalothin50 mM PO4 (sodium phosphate) | 22 | 0.03 | 700 | pH 7 | Open record: KPC-2 variant T237G, cephalothin |
| KPC-2variant T237G | — | cephalothin50 mM PO4 (sodium phosphate) + 0.15 M NaCl | 24 | 0.012 | 2 × 10³ | pH 7 | Open record: KPC-2 variant T237G, cephalothin |
| KPC-2variant T237G | — | cephalothin10 mM HEPES + 0.15 M NaCl | 30 | 0.024 | 1 × 10³ | pH 7 | Open record: KPC-2 variant T237G, cephalothin |
| KPC-2variant T237G | — | cephalothin50 mM Tris-HCl | 37 | 0.012 | 3 × 10³ | pH 7 | Open record: KPC-2 variant T237G, cephalothin |
| TEM-1 | — | cephalothin10 mM PO4 (sodium phosphate) | 98 | 0.19 | 500 | pH 7 | Open record: TEM-1, cephalothin |
| TEM-1 | — | cephalothin50 mM PO4 (sodium phosphate) | 99 | 0.16 | 600 | pH 7 | Open record: TEM-1, cephalothin |
| TEM-1 | — | cephalothin50 mM PO4 (sodium phosphate) + 0.15 M NaCl | 120 | 0.18 | 700 | pH 7 | Open record: TEM-1, cephalothin |
| TEM-1 | — | cephalothin10 mM HEPES + 0.15 M NaCl | 110 | 0.37 | 300 | pH 7 | Open record: TEM-1, cephalothin |
| TEM-1 | — | cephalothin50 mM Tris-HCl | 110 | 0.15 | 700 | pH 7 | Open record: TEM-1, cephalothin |