Values CatLog read from this paper
Bacterial and eukaryotic phenylalanyl-tRNA synthetases catalyze misaminoacylation of tRNA(Phe) with 3,4-dihydroxy-L-phenylalanine
PMID 22035791doi:10.1016/j.chembiol.2011.08.008Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (24 values) from this paper: HsctPheRS (human cytoplasmic phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer), HsmtPheRS (human mitochondrial phenylalanyl-tRNA synthetase, monomer), TtPheRS (phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer) from Homo sapiens, Thermus thermophilus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| HsctPheRS (human cytoplasmic phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer) | Homo sapiens | 3,4-dihydroxy-L-phenylalanine | 0.23 | 0.65 | 0.37 | pH 8, 30 °C | Open record: HsctPheRS (human cytoplasmic phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer), 3,4-dihydroxy-L-phenylalanine |
| HsctPheRS (human cytoplasmic phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer) | Homo sapiens | DL-m-tyrosine | 0.65 | 0.13 | 5 | pH 8, 30 °C | Open record: HsctPheRS (human cytoplasmic phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer), DL-m-tyrosine |
| HsctPheRS (human cytoplasmic phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer) | Homo sapiens | L-phenylalanine | 0.87 | 0.0032 | 270 | pH 8, 30 °C | Open record: HsctPheRS (human cytoplasmic phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer), L-phenylalanine |
| HsmtPheRS (human mitochondrial phenylalanyl-tRNA synthetase, monomer) | Homo sapiens | 3,4-dihydroxy-L-phenylalanine1.3-4 μM E. coli; E. coli | 0.027 | 0.52 | 0.052 | pH 8.5, 37 °C | Open record: HsmtPheRS (human mitochondrial phenylalanyl-tRNA synthetase, monomer), 3,4-dihydroxy-L-phenylalanine |
| HsmtPheRS (human mitochondrial phenylalanyl-tRNA synthetase, monomer) | Homo sapiens | 3,4-dihydroxy-L-phenylalanine2-3 μM human cytoplasmic; human cytoplasmic | 0.057 | 0.6 | 0.095 | pH 8.5, 37 °C | Open record: HsmtPheRS (human mitochondrial phenylalanyl-tRNA synthetase, monomer), 3,4-dihydroxy-L-phenylalanine |
| HsmtPheRS (human mitochondrial phenylalanyl-tRNA synthetase, monomer) | Homo sapiens | L-phenylalanine | 0.075 | 0.0026 | 28 | pH 8.5, 37 °C | Open record: HsmtPheRS (human mitochondrial phenylalanyl-tRNA synthetase, monomer), L-phenylalanine |
| TtPheRS (phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer) | Thermus thermophilus | 3,4-dihydroxy-L-phenylalanine | 0.162 | 0.38 | 0.43 | pH 8.5, 37 °C | Open record: TtPheRS (phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer), 3,4-dihydroxy-L-phenylalanine |
| TtPheRS (phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer) | Thermus thermophilus | L-phenylalanine | 1.12 | 0.0017 | 650 | pH 8.5, 37 °C | Open record: TtPheRS (phenylalanyl-tRNA synthetase, (alpha beta)2 heterotetramer), L-phenylalanine |