Values CatLog read from this paper

Structural and functional analyses of human tryptophan 2,3-dioxygenase

PMID 25066423doi:10.1002/prot.24653Open in Browse

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CatLog read 7 records (21 values) from this paper: tryptophan 2,3-dioxygenase (hTDO) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.13.11.11

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
tryptophan 2,3-dioxygenase (hTDO)	Homo sapiens	L-tryptophanfull-length hTDO (NP_005642)	1.071	0.135	7.93	pH 8, 25 °C	Open record: tryptophan 2,3-dioxygenase (hTDO), L-tryptophan
tryptophan 2,3-dioxygenase (hTDO)	Homo sapiens	L-tryptophanresidues 19-388 (aa 19–388 truncation)	0.976	0.153	6.38	pH 8, 25 °C	Open record: tryptophan 2,3-dioxygenase (hTDO), L-tryptophan
tryptophan 2,3-dioxygenase (hTDO)variant F140A	Homo sapiens	L-tryptophan	0.032	1.531	0.02	pH 8, 25 °C	Open record: tryptophan 2,3-dioxygenase (hTDO) variant F140A, L-tryptophan
tryptophan 2,3-dioxygenase (hTDO)variant R144A	Homo sapiens	L-tryptophan	0.045	0.631	0.07	pH 8, 25 °C	Open record: tryptophan 2,3-dioxygenase (hTDO) variant R144A, L-tryptophan
tryptophan 2,3-dioxygenase (hTDO)variant S151A	Homo sapiens	L-tryptophan	0.105	0.146	0.72	pH 8, 25 °C	Open record: tryptophan 2,3-dioxygenase (hTDO) variant S151A, L-tryptophan
tryptophan 2,3-dioxygenase (hTDO)variant Y42A	Homo sapiens	L-tryptophan	0.01	0.227	0.04	pH 8, 25 °C	Open record: tryptophan 2,3-dioxygenase (hTDO) variant Y42A, L-tryptophan
tryptophan 2,3-dioxygenase (hTDO)variant Y45A	Homo sapiens	L-tryptophan	0.062	0.661	0.09	pH 8, 25 °C	Open record: tryptophan 2,3-dioxygenase (hTDO) variant Y45A, L-tryptophan