Values CatLog read from this paper

Dominant negative role of the glutamic acid residue conserved in the pyruvate kinase M(1) isozyme in the heterotropic allosteric effect involving fructose-1,6-bisphosphate

PMID 10734049doi:10.1074/jbc.275.13.9150Open in Browse

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CatLog read 8 records (8 values) from this paper: pyruvate kinase M1 isozyme (PK-M1) from Rattus norvegicus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.7.1.40

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
pyruvate kinase M1 isozyme (PK-M1)Rattus norvegicusadenosine 5'-diphosphate—0.56—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1), adenosine 5'-diphosphate
pyruvate kinase M1 isozyme (PK-M1)variant A398RRattus norvegicusadenosine 5'-diphosphate—0.5—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1) variant A398R, adenosine 5'-diphosphate
pyruvate kinase M1 isozyme (PK-M1)variant A398R/E432ARattus norvegicusadenosine 5'-diphosphate—0.52—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1) variant A398R/E432A, adenosine 5'-diphosphate
pyruvate kinase M1 isozyme (PK-M1)variant A398R/E432DRattus norvegicusadenosine 5'-diphosphate—0.45—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1) variant A398R/E432D, adenosine 5'-diphosphate
pyruvate kinase M1 isozyme (PK-M1)variant A398R/E432KRattus norvegicusadenosine 5'-diphosphate—0.57—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1) variant A398R/E432K, adenosine 5'-diphosphate
pyruvate kinase M1 isozyme (PK-M1)variant E432ARattus norvegicusadenosine 5'-diphosphate—0.7—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1) variant E432A, adenosine 5'-diphosphate
pyruvate kinase M1 isozyme (PK-M1)variant E432DRattus norvegicusadenosine 5'-diphosphate—0.66—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1) variant E432D, adenosine 5'-diphosphate
pyruvate kinase M1 isozyme (PK-M1)variant E432KRattus norvegicusadenosine 5'-diphosphate—0.62—pH 7.5, 37 °COpen record: pyruvate kinase M1 isozyme (PK-M1) variant E432K, adenosine 5'-diphosphate