Values CatLog read from this paper
A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax
PMID 18519562doi:10.1074/jbc.m803705200Open in Browse
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CatLog read 13 records (39 values) from this paper: nucleoside hydrolase (TvNH, purine-specific) from Trypanosoma vivax.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| nucleoside hydrolase (TvNH, purine-specific) | Trypanosoma vivax | 2-aminopurine riboside | 0.57 | 0.009 | 600 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific), 2-aminopurine riboside |
| nucleoside hydrolase (TvNH, purine-specific) | Trypanosoma vivax | 7-methylguanosine | 1.07 | 5 × 10⁻⁴ | 2.1 × 10⁴ | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific), 7-methylguanosine |
| nucleoside hydrolase (TvNH, purine-specific) | Trypanosoma vivax | guanosine | 2.3 | 0.0023 | 1 × 10³ | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific), guanosine |
| nucleoside hydrolase (TvNH, purine-specific)3G (loop 2 deletion: 13 residues between Met244 and Tyr258 replaced by three Gly) | Trypanosoma vivax | 2-aminopurine riboside | 0.22 | 0.03 | 70 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) 3G (loop 2 deletion: 13 residues between Met244 and Tyr258 replaced by three Gly), 2-aminopurine riboside |
| nucleoside hydrolase (TvNH, purine-specific)3G (loop 2 deletion: 13 residues between Met244 and Tyr258 replaced by three Gly) | Trypanosoma vivax | 7-methylguanosine | 56 | 0.015 | 3.7 × 10⁴ | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) 3G (loop 2 deletion: 13 residues between Met244 and Tyr258 replaced by three Gly), 7-methylguanosine |
| nucleoside hydrolase (TvNH, purine-specific)3G (loop 2 deletion: 13 residues between Met244 and Tyr258 replaced by three Gly) | Trypanosoma vivax | guanosine | 1.52 | 0.266 | 6 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) 3G (loop 2 deletion: 13 residues between Met244 and Tyr258 replaced by three Gly), guanosine |
| nucleoside hydrolase (TvNH, purine-specific)variant C248P | Trypanosoma vivax | guanosine | 1.09 | 0.004 | 270 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) variant C248P, guanosine |
| nucleoside hydrolase (TvNH, purine-specific)variant D253P | Trypanosoma vivax | guanosine | 3.9 | 0.0018 | 2.2 × 10³ | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) variant D253P, guanosine |
| nucleoside hydrolase (TvNH, purine-specific)variant E249P | Trypanosoma vivax | guanosine | 1.7 | 0.003 | 400 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) variant E249P, guanosine |
| nucleoside hydrolase (TvNH, purine-specific)variant H247P | Trypanosoma vivax | guanosine | 4.1 | 0.008 | 500 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) variant H247P, guanosine |
| nucleoside hydrolase (TvNH, purine-specific)variant L250P | Trypanosoma vivax | guanosine | 1.4 | 0.016 | 80 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) variant L250P, guanosine |
| nucleoside hydrolase (TvNH, purine-specific)variant L251P | Trypanosoma vivax | guanosine | 2.5 | 0.021 | 120 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) variant L251P, guanosine |
| nucleoside hydrolase (TvNH, purine-specific)variant R252P | Trypanosoma vivax | guanosine | 13 | 0.024 | 500 | pH 7, 25 °C | Open record: nucleoside hydrolase (TvNH, purine-specific) variant R252P, guanosine |