Values CatLog read from this paper
Kinetic properties and metal content of the metallo-beta-lactamase CcrA harboring selective amino acid substitutions
PMID 10336469doi:10.1074/jbc.274.22.15706Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 24 records (72 values) from this paper: metallo-beta-lactamase CcrA3, metallo-beta-lactamase CcrA1 from Bacteroides fragilis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| metallo-beta-lactamase CcrA1variant C104S/C155V | Bacteroides fragilis | cephaloridine | 58 | 0.0065 | 8.9 × 10³ | pH 7.2 | Open record: metallo-beta-lactamase CcrA1 variant C104S/C155V, cephaloridine |
| metallo-beta-lactamase CcrA1variant C104S/C155V | Bacteroides fragilis | imipenem | 6.1 | 0.0032 | 2 × 10³ | pH 7.2 | Open record: metallo-beta-lactamase CcrA1 variant C104S/C155V, imipenem |
| metallo-beta-lactamase CcrA1variant C104S/C155V | Bacteroides fragilis | penicillin G | 23 | 0.055 | 430 | pH 7.2 | Open record: metallo-beta-lactamase CcrA1 variant C104S/C155V, penicillin G |
| metallo-beta-lactamase CcrA3variant C104R | Bacteroides fragilis | cephaloridine | 46 | 0.033 | 1.4 × 10³ | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant C104R, cephaloridine |
| metallo-beta-lactamase CcrA3variant C104R | Bacteroides fragilis | imipenem | 9.2 | 0.028 | 330 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant C104R, imipenem |
| metallo-beta-lactamase CcrA3variant C104R | Bacteroides fragilis | penicillin G | 54 | 0.085 | 630 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant C104R, penicillin G |
| metallo-beta-lactamase CcrA3variant C181S | Bacteroides fragilis | cephaloridine | 0.13 | 0.055 | 2.4 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant C181S, cephaloridine |
| metallo-beta-lactamase CcrA3variant C181S | Bacteroides fragilis | imipenem | 0.05 | 0.38 | 0.14 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant C181S, imipenem |
| metallo-beta-lactamase CcrA3variant C181S | Bacteroides fragilis | penicillin G | 0.65 | 0.17 | 3.9 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant C181S, penicillin G |
| metallo-beta-lactamase CcrA3variant D103N | Bacteroides fragilis | cephaloridine | 0.28 | 0.017 | 16 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant D103N, cephaloridine |
| metallo-beta-lactamase CcrA3variant D103N | Bacteroides fragilis | imipenem | 3.9 | 0.014 | 280 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant D103N, imipenem |
| metallo-beta-lactamase CcrA3variant D103N | Bacteroides fragilis | penicillin G | 40 | 0.51 | 77 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant D103N, penicillin G |
| metallo-beta-lactamase CcrA3variant H99N | Bacteroides fragilis | cephaloridine | 20 | 0.76 | 26 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant H99N, cephaloridine |
| metallo-beta-lactamase CcrA3variant H99N | Bacteroides fragilis | imipenem | 0.029 | 0.18 | 0.16 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant H99N, imipenem |
| metallo-beta-lactamase CcrA3variant H99N | Bacteroides fragilis | penicillin G | 0.28 | 0.15 | 1.8 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant H99N, penicillin G |
| metallo-beta-lactamase CcrA3variant K184R | Bacteroides fragilis | cephaloridine | 46 | 0.013 | 3.6 × 10³ | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant K184R, cephaloridine |
| metallo-beta-lactamase CcrA3variant K184R | Bacteroides fragilis | imipenem | 110 | 0.7 | 160 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant K184R, imipenem |
| metallo-beta-lactamase CcrA3variant K184R | Bacteroides fragilis | penicillin G | 620 | 0.42 | 1.5 × 10³ | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant K184R, penicillin G |
| metallo-beta-lactamase CcrA3variant N193D | Bacteroides fragilis | cephaloridine | 330 | 0.043 | 7.6 × 10³ | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant N193D, cephaloridine |
| metallo-beta-lactamase CcrA3variant N193D | Bacteroides fragilis | imipenem | 17 | 0.57 | 30 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant N193D, imipenem |
| metallo-beta-lactamase CcrA3variant N193D | Bacteroides fragilis | penicillin G | 790 | 0.93 | 850 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant N193D, penicillin G |
| metallo-beta-lactamase CcrA3variant Δ46–51 | Bacteroides fragilis | cephaloridine | 3.7 | 2.7 | 1.4 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant Δ46–51, cephaloridine |
| metallo-beta-lactamase CcrA3variant Δ46–51 | Bacteroides fragilis | imipenem | 1.8 | 0.51 | 3.5 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant Δ46–51, imipenem |
| metallo-beta-lactamase CcrA3variant Δ46–51 | Bacteroides fragilis | penicillin G | 1.5 | 0.63 | 2.4 | pH 7.2 | Open record: metallo-beta-lactamase CcrA3 variant Δ46–51, penicillin G |