Values CatLog read from this paper
Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis
PMID 19812041doi:10.1074/jbc.m109.053819Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 14 records (40 values) from this paper: TEM-1 beta-lactamase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| TEM-1 beta-lactamase | — | ampicillin | 1085 | 0.038 | 2.9 × 10⁴ | Open record: TEM-1 beta-lactamase, ampicillin | |
| TEM-1 beta-lactamase | — | cephalexin | 13 | 1.162 | 10 | Open record: TEM-1 beta-lactamase, cephalexin | |
| TEM-1 beta-lactamase | — | cephalothin | 146 | 0.182 | 800 | Open record: TEM-1 beta-lactamase, cephalothin | |
| TEM-1 beta-lactamase | — | penicillin G | 950 | 0.028 | 3.4 × 10⁴ | Open record: TEM-1 beta-lactamase, penicillin G | |
| TEM-1 beta-lactamasevariant E166A/N170G | — | ampicillin | 0.9 | 0.024 | 40 | Open record: TEM-1 beta-lactamase variant E166A/N170G, ampicillin | |
| TEM-1 beta-lactamasevariant E166A/N170G | — | penicillin G | 0.8 | 0.02 | 40 | Open record: TEM-1 beta-lactamase variant E166A/N170G, penicillin G | |
| TEM-1 beta-lactamasevariant N170A | — | ampicillin | 22 | 0.013 | 1.7 × 10³ | Open record: TEM-1 beta-lactamase variant N170A, ampicillin | |
| TEM-1 beta-lactamasevariant N170A | — | cephalexin | 1 | 1.561 | 1 | Open record: TEM-1 beta-lactamase variant N170A, cephalexin | |
| TEM-1 beta-lactamasevariant N170A | — | cephalothin | — | — | 4 | Open record: TEM-1 beta-lactamase variant N170A, cephalothin | |
| TEM-1 beta-lactamasevariant N170A | — | penicillin G | 45 | 0.008 | 5.6 × 10³ | Open record: TEM-1 beta-lactamase variant N170A, penicillin G | |
| TEM-1 beta-lactamasevariant N170G | — | ampicillin | 467 | 0.056 | 8.3 × 10³ | Open record: TEM-1 beta-lactamase variant N170G, ampicillin | |
| TEM-1 beta-lactamasevariant N170G | — | cephalexin | 16 | 2.59 | 6 | Open record: TEM-1 beta-lactamase variant N170G, cephalexin | |
| TEM-1 beta-lactamasevariant N170G | — | cephalothin | 31 | 1.501 | 20 | Open record: TEM-1 beta-lactamase variant N170G, cephalothin | |
| TEM-1 beta-lactamasevariant N170G | — | penicillin G | 64 | 0.003 | 2.1 × 10⁴ | Open record: TEM-1 beta-lactamase variant N170G, penicillin G |