Values CatLog read from this paper
Structure, interactions and action of Mycobacterium tuberculosis 3-hydroxyisobutyric acid dehydrogenase
PMID 29959185doi:10.1042/bcj20180271Open in Browse
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CatLog read 9 records (27 values) from this paper: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | (R)-3-hydroxyisobutyric acid | 0.205 | 4.56 | 0.0448 | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), (R)-3-hydroxyisobutyric acid |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | (S)-3-hydroxyisobutyric acid | 1.018 | 0.574 | 1.773 | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), (S)-3-hydroxyisobutyric acid |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | 3-hydroxypropanoic acid | 0.262 | 2.53 | 0.1036 | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), 3-hydroxypropanoic acid |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | D-serine | 0.323 | 579.1 | 5.58 × 10⁻⁴ | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), D-serine |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | L-serine | 0.94 | 21.33 | 0.044 | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), L-serine |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | methyl (R)-3-hydroxy-2-methylpropanoate | 0.002 | 11.87 | 1.68 × 10⁻⁴ | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), methyl (R)-3-hydroxy-2-methylpropanoate |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | methyl (S)-3-hydroxy-2-methylpropanoate | 0.02 | 31.63 | 6.32 × 10⁻⁴ | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), methyl (S)-3-hydroxy-2-methylpropanoate |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | NAD+ | 1.182 | 0.563 | 2.1 | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), NAD+ |
| 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH) | Mycobacterium tuberculosis | NADP+ | 0.29 | 0.582 | 0.498 | pH 8.5, 30 °C | Open record: 3-hydroxyisobutyric acid dehydrogenase (MtHIBADH), NADP+ |