CatLogenzyme kinetics catalog

Values CatLog read from this paper

Properties of recombinant human cytosolic sialidase HsNEU2. The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules

PMID 14613940doi:10.1074/jbc.m308381200Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 14 records (14 values) from this paper: cytosolic sialidase HsNEU2 from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.2.1.18

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
cytosolic sialidase HsNEU2Homo sapiens4-methylumbelliferyl α-N-acetyl-D-neuraminic acid—0.44—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGD1awithout detergent; GD1a as homogeneous micelles—0.91—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGD1awith 0.02% (w/v) Triton X-100—0.14—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGD1bwithout detergent; GD1b as homogeneous micelles—0.59—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGD1bwith 0.02% (w/v) Triton X-100—0.51—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGM1GM1 1-20 nM—1 × 10⁻⁵—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGM1—1.5 × 10⁻⁵—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGM3without detergent; GM3 as homogeneous vesicles—0.4—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGM3with 0.02% (w/v) Triton X-100—0.24—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGT1bwithout detergent; GT1b as homogeneous micelles—0.62—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensGT1bwith 0.02% (w/v) Triton X-100—0.38—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensα2→3 sialosylparaglobosidewithout detergent; α2→3SPG as homogeneous micelles—0.43—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensα2→3 sialosylparaglobosidewith 0.02% (w/v) Triton X-100—0.28—pH 5.6, 37 °COpen
cytosolic sialidase HsNEU2Homo sapiensα2→3 sialyllactose—0.31—pH 5.6, 37 °COpen