Values CatLog read from this paper
The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein
PMID 10373420doi:10.1074/jbc.274.26.18201Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase) | Homo sapiens | 2'-deoxyguanosine 5'-triphosphate | 15.7 | 0.258 | 60 | pH 8, 30 °C | Open record: hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase), 2'-deoxyguanosine 5'-triphosphate |
| hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase) | Homo sapiens | 2-hydroxy-2'-deoxyadenosine 5'-triphosphate | 13.9 | 0.0083 | 1.68 × 10³ | pH 8, 30 °C | Open record: hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase), 2-hydroxy-2'-deoxyadenosine 5'-triphosphate |
| hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase) | Homo sapiens | 2-hydroxy-2'-deoxyadenosine 5'-triphosphate | 4.7 | 0.0057 | 830 | pH 7.2, 30 °C | Open record: hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase), 2-hydroxy-2'-deoxyadenosine 5'-triphosphate |
| hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase) | Homo sapiens | 8-hydroxy-2'-deoxyadenosine 5'-triphosphate | 10.8 | 0.0139 | 780 | pH 8, 30 °C | Open record: hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase), 8-hydroxy-2'-deoxyadenosine 5'-triphosphate |
| hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase) | Homo sapiens | 8-hydroxy-2'-deoxyguanosine 5'-triphosphate | 12.3 | 0.0152 | 810 | pH 8, 30 °C | Open record: hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase), 8-hydroxy-2'-deoxyguanosine 5'-triphosphate |
| hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase) | Homo sapiens | 8-hydroxy-2'-deoxyguanosine 5'-triphosphate | 2.1 | 0.0128 | 160 | pH 7.2, 30 °C | Open record: hMTH1 (human MutT homologue, 8-OH-dGTPase / 2-OH-dATPase), 8-hydroxy-2'-deoxyguanosine 5'-triphosphate |