Values CatLog read from this paper

A direct substrate-substrate interaction found in the kinase domain of the bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

PMID 17499765doi:10.1016/j.jmb.2007.03.038Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 6 records (9 values) from this paper: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activity from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 3 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 2.7.1.105, EC 3.1.3.46

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activityHomo sapiensATP—0.0169—pH 8.5, 25 °COpen record: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activity, ATP
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activityHomo sapiensfructose-6-phosphate0.140.010214 calc.pH 8.5, 25 °COpen record: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activity, fructose-6-phosphate
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activityvariant A44GHomo sapiensATP—8.7 × 10⁻⁴—pH 8.5, 25 °COpen record: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activity variant A44G, ATP
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activityvariant A44GHomo sapiensfructose-6-phosphate0.190.003850 calc.pH 8.5, 25 °COpen record: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activity variant A44G, fructose-6-phosphate
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activityvariant A44VHomo sapiensATP—0.1402—pH 8.5, 25 °COpen record: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activity variant A44V, ATP
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activityvariant A44VHomo sapiensfructose-6-phosphate0.170.2040.83 calc.pH 8.5, 25 °COpen record: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, inducible isoform), 6-phosphofructo-2-kinase (2-Kase) activity variant A44V, fructose-6-phosphate