Values CatLog read from this paper
Structural and biochemical characterization of Siw14: A protein-tyrosine phosphatase fold that metabolizes inositol pyrophosphates
PMID 29540476doi:10.1074/jbc.ra117.001670Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 13 records (39 values) from this paper: Siw14 from Saccharomyces cerevisiae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Siw14 | Saccharomyces cerevisiae | 1,5-bisdiphosphoinositol 2,3,4,6-tetrakisphosphate | 0.63 | 0.0101 | 62 | pH 7.2, 30 °C | Open record: Siw14, 1,5-bisdiphosphoinositol 2,3,4,6-tetrakisphosphate |
| Siw14 | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 1.31 | 0.0104 | 125 | pH 7.2, 30 °C | Open record: Siw14, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14 | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphateresidues 116-281 (N-terminally truncated catalytic core) | 1.32 | 0.0116 | 114 | pH 7.2, 30 °C | Open record: Siw14, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14 | Saccharomyces cerevisiae | 5-diphosphoinositol 1,3,4,6-tetrakisphosphate | 0.77 | 0.0568 | 14 | pH 7.2, 30 °C | Open record: Siw14, 5-diphosphoinositol 1,3,4,6-tetrakisphosphate |
| Siw14variant E185A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.8 | 0.0122 | 66 | pH 7.2, 30 °C | Open record: Siw14 variant E185A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant H219A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.38 | 0.017 | 22 | pH 7.2, 30 °C | Open record: Siw14 variant H219A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant K184A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.46 | 0.0471 | 10 | pH 7.2, 30 °C | Open record: Siw14 variant K184A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant K218A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.48 | 0.0286 | 17 | pH 7.2, 30 °C | Open record: Siw14 variant K218A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant K250A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.21 | 0.0326 | 6 | pH 7.2, 30 °C | Open record: Siw14 variant K250A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant N183A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.57 | 0.0102 | 56 | pH 7.2, 30 °C | Open record: Siw14 variant N183A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant N215A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.29 | 0.007 | 41 | pH 7.2, 30 °C | Open record: Siw14 variant N215A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant R216A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 1.26 | 0.0145 | 87 | pH 7.2, 30 °C | Open record: Siw14 variant R216A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |
| Siw14variant R252A | Saccharomyces cerevisiae | 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate | 0.35 | 0.0481 | 7 | pH 7.2, 30 °C | Open record: Siw14 variant R252A, 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate |