Values CatLog read from this paper
Analysis of tissue plasminogen activator specificity using peptidyl fluorogenic substrates
PMID 9047311doi:10.1021/bi9617670Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 76 records (228 values) from this paper: tissue-type plasminogen activator (tPA), tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | (p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 1.47 | 0.39 | 3.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), (p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.057 | 0.041 | 1.4 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.31 | 0.098 | 3.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.089 | 0.069 | 1.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.021 | 0.0074 | 2.9 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.074 | 0.036 | 2.1 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.044 | 0.016 | 2.7 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.082 | 0.058 | 1.4 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.71 | 0.11 | 6.4 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | L-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.04 | 0.97 | 0.04 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), L-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | L-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.08 | 0.46 | 0.18 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), L-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.097 | 0.015 | 6.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.54 | 0.066 | 8.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.53 | 0.36 | 1.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.1 | 0.03 | 3.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.15 | 0.047 | 3.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.49 | 0.091 | 5.4 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.34 | 0.14 | 2.4 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.25 | 0.026 | 9.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-L-(p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 1.03 | 0.071 | 14.6 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-L-(p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-L-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.011 | 0.047 | 0.24 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-L-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA) | — | tert-butyloxycarbonyl-L-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.084 | 0.1 | 0.83 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant sc-tPA/tc-tPA mixture (80% sc-tPA, 20% tc-tPA), tert-butyloxycarbonyl-L-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | (p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.37 | 0.011 | 32.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), (p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.034 | 0.011 | 3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.17 | 0.012 | 14.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.1 | 0.017 | 6.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.018 | 0.01 | 1.9 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-diethyl (Table 4: D-FPR-ANSNR1R2 with R1 = C2H5, R2 = C2H5) | 0.14 | 0.12 | 1.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-diethyl (Table 4: D-FPR-ANSNR1R2 with R1 = C2H5, R2 = C2H5) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-hexamethylene (R1R2 = (CH2)6 ring) (Table 4: D-FPR-ANSNR1R2 with R1R2 = (CH2)6) | 0.22 | 0.096 | 2.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-hexamethylene (R1R2 = (CH2)6 ring) (Table 4: D-FPR-ANSNR1R2 with R1R2 = (CH2)6) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(2-methoxyethyl) (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C2H4OCH3) | 0.66 | 0.14 | 4.7 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(2-methoxyethyl) (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C2H4OCH3) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(methoxycarbonylmethyl), i.e. glycine methyl ester (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = CH2COOCH3) | 0.15 | 0.029 | 5.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(methoxycarbonylmethyl), i.e. glycine methyl ester (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = CH2COOCH3) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-benzyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C6H5CH2) | 0.54 | 0.025 | 21.6 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-benzyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C6H5CH2) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.51 | 0.077 | 6.6 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = c-C6H11) | 0.32 | 0.088 | 3.6 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = c-C6H11) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-isopropyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = i-C3H7) | 0.2 | 0.074 | 2.7 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-isopropyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = i-C3H7) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C4H9) | 0.47 | 0.048 | 9.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C4H9) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-hexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C6H13) | 3.6 | 0.095 | 37.9 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-hexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C6H13) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-tert-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = t-C4H9) | 0.94 | 0.084 | 11.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-tert-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = t-C4H9) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.025 | 0.0078 | 3.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.19 | 0.033 | 5.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.16 | 0.0081 | 20.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.04 | 0.0085 | 4.7 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.2 | 0.0088 | 23.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.097 | 0.013 | 7.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.047 | 0.013 | 3.6 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.017 | 0.0026 | 6.4 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.15 | 0.032 | 4.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.18 | 0.014 | 12.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.25 | 0.015 | 16.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA)variant two-chain tPA (tc-tPA) | — | tert-butyloxycarbonyl-L-(p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.44 | 0.0066 | 66.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) variant two-chain tPA (tc-tPA), tert-butyloxycarbonyl-L-(p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | (p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.099 | 0.026 | 3.7 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), (p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.0084 | 0.011 | 0.71 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.061 | 0.04 | 1.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.019 | 0.014 | 1.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-diethyl (Table 4: D-FPR-ANSNR1R2 with R1 = C2H5, R2 = C2H5) | 0.09 | 0.32 | 0.28 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-diethyl (Table 4: D-FPR-ANSNR1R2 with R1 = C2H5, R2 = C2H5) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-hexamethylene (R1R2 = (CH2)6 ring) (Table 4: D-FPR-ANSNR1R2 with R1R2 = (CH2)6) | 0.13 | 0.25 | 0.52 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N,N-hexamethylene (R1R2 = (CH2)6 ring) (Table 4: D-FPR-ANSNR1R2 with R1R2 = (CH2)6) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(2-methoxyethyl) (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C2H4OCH3) | 0.27 | 0.18 | 1.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(2-methoxyethyl) (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C2H4OCH3) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(methoxycarbonylmethyl), i.e. glycine methyl ester (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = CH2COOCH3) | 0.083 | 0.063 | 1.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-(methoxycarbonylmethyl), i.e. glycine methyl ester (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = CH2COOCH3) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-benzyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C6H5CH2) | 0.45 | 0.063 | 7.1 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-benzyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = C6H5CH2) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.016 | 0.0057 | 2.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = c-C6H11) | 0.15 | 0.15 | 1 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = c-C6H11) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-isopropyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = i-C3H7) | 0.29 | 0.33 | 0.88 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-isopropyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = i-C3H7) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C4H9) | 0.33 | 0.12 | 2.8 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C4H9) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-hexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C6H13) | 1.1 | 0.099 | 11.1 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-n-hexyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = n-C6H13) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-tert-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = t-C4H9) | 0.25 | 0.079 | 3.2 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-tert-butyl (Table 4: D-FPR-ANSNR1R2 with R1 = H, R2 = t-C4H9) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.011 | 0.0073 | 1.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.021 | 0.022 | 0.95 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.059 | 0.025 | 2.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) | 0.012 | 0.023 | 0.51 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-D-Leu-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-cyclohexyl (C6H11; c-C6H11 per Table 4) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.038 | 0.015 | 2.5 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-D-Leu-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.022 | 0.02 | 1.1 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-D-Leu-Ser-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) | 0.01 | 0.017 | 0.6 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-D-Phe-Leu-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C3H7 (propyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.019 | 0.012 | 1.7 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-D-Phe-Val-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.036 | 0.019 | 1.9 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-D-Val-Gly-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) | 0.065 | 0.029 | 2.3 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-D-Val-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-C4H9 (butyl, isomer not stated) |
| tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA) | — | tert-butyloxycarbonyl-L-(p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl | 0.11 | 0.016 | 7.1 | pH 7.4, 25 °C | Open record: tissue-type plasminogen activator (tPA) single-chain tPA (sc-tPA), tert-butyloxycarbonyl-L-(p-fluoro)Phe-Pro-Arg 6-amino-1-naphthalenesulfonamide (ANSN) leaving group, sulfonamide N-ethyl |