CatLogenzyme kinetics catalog

Values CatLog read from this paper

Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)

PMID 31784620doi:10.1038/s41598-019-54384-8Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 18 records (54 values) from this paper: beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.4.3.2, EC 2.4.3.4

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant C59S/C64SHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.280.02114.2pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant C59S/C64SHomo sapiensCMP-Neu5Ac2.250.12118.6pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N147SHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.80.2113.78pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N147SHomo sapiensCMP-Neu5Ac1.250.6681.87pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N170AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.650.0966.77pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N170AHomo sapiensCMP-Neu5Ac0.620.1843.35pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant S148AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.320.10522.07pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant S148AHomo sapiensCMP-Neu5Ac3.650.4817.58pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.421.3881.75pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315AHomo sapiensCMP-Neu5Ac1.050.185.8pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315YHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.20.5490.37pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315YHomo sapiensCMP-Neu5Ac0.130.2710.47pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y191AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.470.4441.05pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y191AHomo sapiensCMP-Neu5Ac0.630.8760.72pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.970.8543.47pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230AHomo sapiensCMP-Neu5Ac2.50.20512.2pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230FHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside3.470.3529.85pH 7.4, 37 °COpen
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230FHomo sapiensCMP-Neu5Ac2.70.17615.3pH 7.4, 37 °COpen