CatLogenzyme kinetics catalog

EC 2.4.3.2: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase

TransferasesOpen in Browse

CatLog read 21 records for EC 2.4.3.2 from 2 papers, for 1 organism. Names in these papers: beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1), ST3Gal-IV.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 14 records for EC 2.4.3.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.3.2 in Browse.

Papers

PaperOrganismsRecords
Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)Homo sapiens18
Selective Engineering of Linkage-Specific α2,6-N-Linked Sialoproteins Using Sydnone-Modified Sialic Acid Bioorthogonal ReportersHomo sapiens3

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant C59S/C64SHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.280.02114.2pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant C59S/C64SHomo sapiensCMP-Neu5Ac2.250.12118.6pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N147SHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.80.2113.78pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N147SHomo sapiensCMP-Neu5Ac1.250.6681.87pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N170AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.650.0966.77pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant N170AHomo sapiensCMP-Neu5Ac0.620.1843.35pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant S148AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.320.10522.07pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant S148AHomo sapiensCMP-Neu5Ac3.650.4817.58pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.421.3881.75pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315AHomo sapiensCMP-Neu5Ac1.050.185.8pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315YHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.20.5490.37pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant V315YHomo sapiensCMP-Neu5Ac0.130.2710.47pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y191AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside0.470.4441.05pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y191AHomo sapiensCMP-Neu5Ac0.630.8760.72pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230AHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside2.970.8543.47pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230AHomo sapiensCMP-Neu5Ac2.50.20512.2pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230FHomo sapiensbenzyl 2-acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside3.470.3529.85pH 7.4, 37 °CPMID 31784620Open
beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)variant Y230FHomo sapiensCMP-Neu5Ac2.70.17615.3pH 7.4, 37 °CPMID 31784620Open
ST3Gal-IVHomo sapiensCMP-Neu5Ac0.0230.30.078PMID 30706985Open
ST3Gal-IVHomo sapiensCMP-Neu9Az0.0570.2370.238PMID 30706985Open
ST3Gal-IVHomo sapiensCMP-Neu9NSydCl0.0873.0570.028PMID 30706985Open