Values CatLog read from this paper

Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis

PMID 19776021doi:10.1074/jbc.m109.046821Open in Browse

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CatLog read 18 records (54 values) from this paper: homocitrate synthase (SpHCS) from Schizosaccharomyces pombe.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.3.3.14

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
homocitrate synthase (SpHCS)	Schizosaccharomyces pombe	2-oxoglutarate	5.13	0.159	32.3	pH 7.5	Open record: homocitrate synthase (SpHCS), 2-oxoglutarate
homocitrate synthase (SpHCS)	Schizosaccharomyces pombe	acetyl-CoA	4.98	0.0107	467	pH 7.5	Open record: homocitrate synthase (SpHCS), acetyl-CoA
homocitrate synthase (SpHCS)variant E74Q	Schizosaccharomyces pombe	2-oxoglutarate	0.778	0.791	0.983	pH 7.5	Open record: homocitrate synthase (SpHCS) variant E74Q, 2-oxoglutarate
homocitrate synthase (SpHCS)variant E74Q	Schizosaccharomyces pombe	acetyl-CoA	0.742	0.0307	24.2	pH 7.5	Open record: homocitrate synthase (SpHCS) variant E74Q, acetyl-CoA
homocitrate synthase (SpHCS)variant H103A	Schizosaccharomyces pombe	2-oxoglutarate	0.303	3.56	0.0852	pH 7.5	Open record: homocitrate synthase (SpHCS) variant H103A, 2-oxoglutarate
homocitrate synthase (SpHCS)variant H103A	Schizosaccharomyces pombe	acetyl-CoA	0.333	0.0352	9.47	pH 7.5	Open record: homocitrate synthase (SpHCS) variant H103A, acetyl-CoA
homocitrate synthase (SpHCS)variant Q47A	Schizosaccharomyces pombe	2-oxoglutarate	0.558	4.94	0.113	pH 7.5	Open record: homocitrate synthase (SpHCS) variant Q47A, 2-oxoglutarate
homocitrate synthase (SpHCS)variant Q47A	Schizosaccharomyces pombe	acetyl-CoA	0.583	0.0576	10.13	pH 7.5	Open record: homocitrate synthase (SpHCS) variant Q47A, acetyl-CoA
homocitrate synthase (SpHCS)variant R163K	Schizosaccharomyces pombe	2-oxoglutarate	0.435	24.4	0.0178	pH 7.5	Open record: homocitrate synthase (SpHCS) variant R163K, 2-oxoglutarate
homocitrate synthase (SpHCS)variant R163K	Schizosaccharomyces pombe	acetyl-CoA	0.565	0.146	3.87	pH 7.5	Open record: homocitrate synthase (SpHCS) variant R163K, acetyl-CoA
homocitrate synthase (SpHCS)variant S165A	Schizosaccharomyces pombe	2-oxoglutarate	2.67	0.536	4.97	pH 7.5	Open record: homocitrate synthase (SpHCS) variant S165A, 2-oxoglutarate
homocitrate synthase (SpHCS)variant S165A	Schizosaccharomyces pombe	acetyl-CoA	2.63	0.0186	142	pH 7.5	Open record: homocitrate synthase (SpHCS) variant S165A, acetyl-CoA
homocitrate synthase (SpHCS)variant T197A	Schizosaccharomyces pombe	2-oxoglutarate	0.198	0.341	0.582	pH 7.5	Open record: homocitrate synthase (SpHCS) variant T197A, 2-oxoglutarate
homocitrate synthase (SpHCS)variant T197A	Schizosaccharomyces pombe	acetyl-CoA	0.178	0.00744	24	pH 7.5	Open record: homocitrate synthase (SpHCS) variant T197A, acetyl-CoA
homocitrate synthase (SpHCS)variant T197S	Schizosaccharomyces pombe	2-oxoglutarate	2.28	0.229	9.95	pH 7.5	Open record: homocitrate synthase (SpHCS) variant T197S, 2-oxoglutarate
homocitrate synthase (SpHCS)variant T197S	Schizosaccharomyces pombe	acetyl-CoA	2.07	0.006	343	pH 7.5	Open record: homocitrate synthase (SpHCS) variant T197S, acetyl-CoA
homocitrate synthase (SpHCS)variant Y332F	Schizosaccharomyces pombe	2-oxoglutarate	0.345	0.461	0.748	pH 7.5	Open record: homocitrate synthase (SpHCS) variant Y332F, 2-oxoglutarate
homocitrate synthase (SpHCS)variant Y332F	Schizosaccharomyces pombe	acetyl-CoA	0.392	0.04	9.8	pH 7.5	Open record: homocitrate synthase (SpHCS) variant Y332F, acetyl-CoA