Values CatLog read from this paper
Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase
PMID 7761851doi:10.1126/science.7761851Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (23 values) from this paper: isocitrate dehydrogenase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| isocitrate dehydrogenase | — | D-isocitrate | 38.3 | 2.8 | 14 calc. | pH 7.5 | Open record: isocitrate dehydrogenase, D-isocitrate |
| isocitrate dehydrogenase | — | oxalosuccinatedecarboxylation of oxalosuccinate to alpha-ketoglutarate | 28.3 | 5.2 | 5.4 | pH 7.5 | Open record: isocitrate dehydrogenase, oxalosuccinate |
| isocitrate dehydrogenase | — | oxalosuccinatecosubstrate NADPH | 1.72 | 2.81 | 0.61 | pH 7.5 | Open record: isocitrate dehydrogenase, oxalosuccinate |
| isocitrate dehydrogenasevariant K230M | — | D-isocitrate | 0.78 | 10.9 | 0.072 | pH 7.5 | Open record: isocitrate dehydrogenase variant K230M, D-isocitrate |
| isocitrate dehydrogenasevariant K230M | — | oxalosuccinate | 0.421 | 32 | 0.013 | pH 7.5 | Open record: isocitrate dehydrogenase variant K230M, oxalosuccinate |
| isocitrate dehydrogenasevariant Y160F | — | D-isocitrate | 0.276 | 0.23 | 1.2 | pH 7.5 | Open record: isocitrate dehydrogenase variant Y160F, D-isocitrate |
| isocitrate dehydrogenasevariant Y160F | — | oxalosuccinatedecarboxylation of oxalosuccinate to alpha-ketoglutarate | 33.8 | 6.1 | 5.54 | pH 7.5 | Open record: isocitrate dehydrogenase variant Y160F, oxalosuccinate |
| isocitrate dehydrogenasevariant Y160F | — | oxalosuccinatecosubstrate NADPH | 0.031 | 6.135 | 0.005 | pH 7.5 | Open record: isocitrate dehydrogenase variant Y160F, oxalosuccinate |