CatLogenzyme kinetics catalog

Values CatLog read from this paper

Possible role of inter-domain salt bridges in oligopeptidase B from Trypanosoma brucei: critical role of Glu172 of non-catalytic β-propeller domain in catalytic activity and Glu490 of catalytic…

PMID 23946505doi:10.1093/jb/mvt077Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 25 records (75 values) from this paper: oligopeptidase B (Tb OPB) from Trypanosoma brucei.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.21.83

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
oligopeptidase B (Tb OPB)Trypanosoma bruceicarbobenzoxy-Arg-Arg-4-methylcoumaryl 7-amide5.822.7 × 10⁻⁴2.16 × 10⁴Open
oligopeptidase B (Tb OPB)Trypanosoma bruceit-butyloxycarbonyl-Arg-Thr-Lys-Arg-4-methylcoumaryl 7-amide5.166.3 × 10⁻⁴8.91 × 10³Open
oligopeptidase B (Tb OPB)Trypanosoma bruceit-butyloxycarbonyl-Leu-Lys-Arg-4-methylcoumaryl 7-amide3.360.001172.87 × 10³Open
oligopeptidase B (Tb OPB)variant E172QTrypanosoma bruceibenzoyl-Arg-4-methylcoumaryl 7-amide6.610.0212310Open
oligopeptidase B (Tb OPB)variant E172QTrypanosoma bruceicarbobenzoxy-Arg-Arg-4-methylcoumaryl 7-amide8.720.005961.46 × 10³Open
oligopeptidase B (Tb OPB)variant E172QTrypanosoma bruceicarbobenzoxy-Phe-Arg-4-methylcoumaryl 7-amide3.910.034120Open
oligopeptidase B (Tb OPB)variant E172QTrypanosoma bruceit-butyloxycarbonyl-Arg-Thr-Lys-Arg-4-methylcoumaryl 7-amide1.380.0106310Open
oligopeptidase B (Tb OPB)variant E172QTrypanosoma bruceit-butyloxycarbonyl-Leu-Lys-Arg-4-methylcoumaryl 7-amide1.170.017766Open
oligopeptidase B (Tb OPB)variant E490QTrypanosoma bruceibenzoyl-Arg-4-methylcoumaryl 7-amide33.90.008464.01 × 10³Open
oligopeptidase B (Tb OPB)variant E490QTrypanosoma bruceicarbobenzoxy-Arg-Arg-4-methylcoumaryl 7-amide14.34.3 × 10⁻⁴3.33 × 10⁴Open
oligopeptidase B (Tb OPB)variant E490QTrypanosoma bruceicarbobenzoxy-Phe-Arg-4-methylcoumaryl 7-amide9.550.0108880Open
oligopeptidase B (Tb OPB)variant E490QTrypanosoma bruceit-butyloxycarbonyl-Arg-Thr-Lys-Arg-4-methylcoumaryl 7-amide100.00119.09 × 10³Open
oligopeptidase B (Tb OPB)variant E490QTrypanosoma bruceit-butyloxycarbonyl-Leu-Lys-Arg-4-methylcoumaryl 7-amide12.30.003653.37 × 10³Open
oligopeptidase B (Tb OPB)variant E524QTrypanosoma bruceibenzoyl-Arg-4-methylcoumaryl 7-amide22.80.005644.04 × 10³Open
oligopeptidase B (Tb OPB)variant E524QTrypanosoma bruceicarbobenzoxy-Arg-Arg-4-methylcoumaryl 7-amide11.81.7 × 10⁻⁴6.94 × 10⁴Open
oligopeptidase B (Tb OPB)variant E524QTrypanosoma bruceicarbobenzoxy-Phe-Arg-4-methylcoumaryl 7-amide70.004211.66 × 10³Open
oligopeptidase B (Tb OPB)variant E524QTrypanosoma bruceit-butyloxycarbonyl-Arg-Thr-Lys-Arg-4-methylcoumaryl 7-amide6.642.9 × 10⁻⁴2.29 × 10⁴Open
oligopeptidase B (Tb OPB)variant E524QTrypanosoma bruceit-butyloxycarbonyl-Leu-Lys-Arg-4-methylcoumaryl 7-amide6.933.6 × 10⁻⁴1.93 × 10⁴Open
oligopeptidase B (Tb OPB)variant R354ATrypanosoma bruceicarbobenzoxy-Phe-Arg-4-methylcoumaryl 7-amide11.70.006591.82 × 10³Open
oligopeptidase B (Tb OPB)variant R650ATrypanosoma bruceicarbobenzoxy-Phe-Arg-4-methylcoumaryl 7-amide3.030.114327Open
oligopeptidase B (Tb OPB)variant R689ATrypanosoma bruceibenzoyl-Arg-4-methylcoumaryl 7-amide13.40.0411330Open
oligopeptidase B (Tb OPB)variant R689ATrypanosoma bruceicarbobenzoxy-Arg-Arg-4-methylcoumaryl 7-amide11.40.004932.31 × 10³Open
oligopeptidase B (Tb OPB)variant R689ATrypanosoma bruceicarbobenzoxy-Phe-Arg-4-methylcoumaryl 7-amide3.620.0185190Open
oligopeptidase B (Tb OPB)variant R689ATrypanosoma bruceit-butyloxycarbonyl-Arg-Thr-Lys-Arg-4-methylcoumaryl 7-amide4.257.8 × 10⁻⁴5.45 × 10³Open
oligopeptidase B (Tb OPB)variant R689ATrypanosoma bruceit-butyloxycarbonyl-Leu-Lys-Arg-4-methylcoumaryl 7-amide2.910.00856340Open