Values CatLog read from this paper
Identification of the catalytically important histidine of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
PMID 1634543doi:10.1016/s0021-9258(18)42146-1Open in Browse
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CatLog read 18 records (18 values) from this paper: 3-hydroxy-3-methylglutaryl-coenzyme A reductase from Pseudomonas mevalonii.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Pseudomonas mevalonii | (R,S)-mevalonate | — | 0.45 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, (R,S)-mevalonate |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Pseudomonas mevalonii | (R,S)-mevalonate | — | 0.32 | — | pH 11, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, (R,S)-mevalonate |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Pseudomonas mevalonii | coenzyme A | — | 0.05 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, coenzyme A |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Pseudomonas mevalonii | coenzyme A | — | 0.24 | — | pH 11, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, coenzyme A |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Pseudomonas mevalonii | NAD+ | — | 0.22 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, NAD+ |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Pseudomonas mevalonii | NAD+ | — | 0.15 | — | pH 11, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, NAD+ |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381A | Pseudomonas mevalonii | (R,S)-mevalonate | — | 0.27 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381A, (R,S)-mevalonate |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381A | Pseudomonas mevalonii | coenzyme A | — | 0.03 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381A, coenzyme A |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381A | Pseudomonas mevalonii | NAD+ | — | 0.14 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381A, NAD+ |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381K | Pseudomonas mevalonii | (R,S)-mevalonate | — | 0.75 | — | pH 11, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381K, (R,S)-mevalonate |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381K | Pseudomonas mevalonii | coenzyme A | — | 0.5 | — | pH 11, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381K, coenzyme A |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381K | Pseudomonas mevalonii | NAD+ | — | 1.23 | — | pH 11, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381K, NAD+ |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381N | Pseudomonas mevalonii | (R,S)-mevalonate | — | 3.7 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381N, (R,S)-mevalonate |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381N | Pseudomonas mevalonii | coenzyme A | — | 0.2 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381N, coenzyme A |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381N | Pseudomonas mevalonii | NAD+ | — | 0.81 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381N, NAD+ |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381Q | Pseudomonas mevalonii | (R,S)-mevalonate | — | 0.71 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381Q, (R,S)-mevalonate |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381Q | Pseudomonas mevalonii | coenzyme A | — | 0.11 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381Q, coenzyme A |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductasevariant H381Q | Pseudomonas mevalonii | NAD+ | — | 0.62 | — | pH 8.1, 37 °C | Open record: 3-hydroxy-3-methylglutaryl-coenzyme A reductase variant H381Q, NAD+ |