Values CatLog read from this paper
Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development
PMID 33139328doi:10.1074/jbc.ra120.014005Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (30 values) from this paper: dUTPase (ASFV dUTPase, aDUT), dUTPase (swine dUTPase, sDUT) from African swine fever virus, Sus scrofa.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dUTPase (ASFV dUTPase, aDUT) | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 4.37 | 9.8 × 10⁻⁴ | 4.46 × 10³ | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT), 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant D29A | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 0.31 | 0.00689 | 46.2 | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant D29A, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant F154Y | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 1.5 | 0.02645 | 56 | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant F154Y, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant I90A | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 0.75 | 4.7 × 10⁻⁴ | 1.58 × 10³ | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant I90A, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant L89A | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 2.94 | 0.00544 | 540 | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant L89A, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant Q120A | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 0.58 | 0.01676 | 35.1 | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant Q120A, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant R149K | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 0.15 | 0.00451 | 33 | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant R149K, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant S72A | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 0.48 | 0.00489 | 98.5 | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant S72A, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (ASFV dUTPase, aDUT)variant S73A | African swine fever virus | 2'-deoxyuridine 5'-triphosphate | 5.58 | 0.00416 | 1.34 × 10³ | pH 7.5, 25 °C | Open record: dUTPase (ASFV dUTPase, aDUT) variant S73A, 2'-deoxyuridine 5'-triphosphate |
| dUTPase (swine dUTPase, sDUT) | Sus scrofa | 2'-deoxyuridine 5'-triphosphate | 5.58 | 5.8 × 10⁻⁴ | 9.6 × 10³ | pH 7.5, 25 °C | Open record: dUTPase (swine dUTPase, sDUT), 2'-deoxyuridine 5'-triphosphate |