Values CatLog read from this paper
Interplay between amino acid residues at positions 192 and 115 in modulating hydrolytic activities of human paraoxonase 1
PMID 25107406doi:10.1016/j.biochi.2014.07.024Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 13 records (39 values) from this paper: human paraoxonase 1 (h-PON1), Chi-PON1 (chimeric PON1, G3C9 variant) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 3.1.1.2, EC 3.1.1.25, EC 3.1.8.1
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Chi-PON1 (chimeric PON1, G3C9 variant)variant G3C9 | — | delta-valerolactone | 49 | 1.8 | 27.3 | pH 8.3, 25 °C | Open record: Chi-PON1 (chimeric PON1, G3C9 variant) variant G3C9, delta-valerolactone |
| Chi-PON1 (chimeric PON1, G3C9 variant)variant G3C9 | — | paraoxon-ethyl | 0.8 | 0.9 | 0.9 | pH 8, 25 °C | Open record: Chi-PON1 (chimeric PON1, G3C9 variant) variant G3C9, paraoxon-ethyl |
| Chi-PON1 (chimeric PON1, G3C9 variant)variant G3C9 | — | phenyl acetate | 1524 | 2.3 | 662.5 | pH 8, 25 °C | Open record: Chi-PON1 (chimeric PON1, G3C9 variant) variant G3C9, phenyl acetate |
| human paraoxonase 1 (h-PON1) | Homo sapiens | delta-valerolactone | 29.8 | 1.5 | 19.8 | pH 8.3, 25 °C | Open record: human paraoxonase 1 (h-PON1), delta-valerolactone |
| human paraoxonase 1 (h-PON1) | Homo sapiens | paraoxon-ethyl | 0.9 | 1.2 | 0.7 | pH 8, 25 °C | Open record: human paraoxonase 1 (h-PON1), paraoxon-ethyl |
| human paraoxonase 1 (h-PON1) | Homo sapiens | phenyl acetate | 843.6 | 2.1 | 401.7 | pH 8, 25 °C | Open record: human paraoxonase 1 (h-PON1), phenyl acetate |
| human paraoxonase 1 (h-PON1)variant H115W | Homo sapiens | delta-valerolactone | 0.5 | 0.4 | 1.3 | pH 8.3, 25 °C | Open record: human paraoxonase 1 (h-PON1) variant H115W, delta-valerolactone |
| human paraoxonase 1 (h-PON1)variant H115W | Homo sapiens | paraoxon-ethyl | 6 | 0.9 | 6.6 | pH 8, 25 °C | Open record: human paraoxonase 1 (h-PON1) variant H115W, paraoxon-ethyl |
| human paraoxonase 1 (h-PON1)variant H115W | Homo sapiens | phenyl acetate | 525.8 | 10.8 | 48.6 | pH 8, 25 °C | Open record: human paraoxonase 1 (h-PON1) variant H115W, phenyl acetate |
| human paraoxonase 1 (h-PON1)variant H115W/R192K | Homo sapiens | delta-valerolactone | 0.9 | 0.5 | 1.9 | pH 8.3, 25 °C | Open record: human paraoxonase 1 (h-PON1) variant H115W/R192K, delta-valerolactone |
| human paraoxonase 1 (h-PON1)variant H115W/R192K | Homo sapiens | paraoxon-ethyl | 10.7 | 0.9 | 10.7 | pH 8, 25 °C | Open record: human paraoxonase 1 (h-PON1) variant H115W/R192K, paraoxon-ethyl |
| human paraoxonase 1 (h-PON1)variant H115W/R192K | Homo sapiens | phenyl acetate | 759 | 4.1 | 185.6 | pH 8, 25 °C | Open record: human paraoxonase 1 (h-PON1) variant H115W/R192K, phenyl acetate |
| human paraoxonase 1 (h-PON1)variant H115W/R192Q | Homo sapiens | paraoxon-ethyl | 3.8 | 0.8 | 4.6 | pH 8, 25 °C | Open record: human paraoxonase 1 (h-PON1) variant H115W/R192Q, paraoxon-ethyl |