Values CatLog read from this paper
A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines
PMID 11927571doi:10.1093/emboj/21.7.1873Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 35 records (99 values) from this paper: deoxyribonucleoside kinase (Dm-dNK) from Drosophila melanogaster.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| deoxyribonucleoside kinase (Dm-dNK) | Drosophila melanogaster | 1-beta-D-arabinofuranosylcytosine | 2.9 | 0.0243 | 120 | Open record: deoxyribonucleoside kinase (Dm-dNK), 1-beta-D-arabinofuranosylcytosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant A110D | Drosophila melanogaster | deoxyadenosine | 0.084 | 0.2387 | 0.352 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant A110D, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant A110D | Drosophila melanogaster | deoxycytidine | 0.27 | 0.091 | 2.967 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant A110D, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant A110D | Drosophila melanogaster | deoxyguanosine | 0.073 | 0.2569 | 0.284 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant A110D, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant A110D | Drosophila melanogaster | thymidine | 0.35 | 0.064 | 5.468 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant A110D, thymidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R | Drosophila melanogaster | deoxyadenosine | 1.88 | 2.088 | 0.9 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R | Drosophila melanogaster | deoxycytidine | 7.5 | 1.039 | 7.218 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R | Drosophila melanogaster | deoxyguanosine | 2.7 | — | — | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R | Drosophila melanogaster | thymidine | 0.13 | 0.237 | 0.548 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R, thymidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R/A110D | Drosophila melanogaster | deoxyadenosine | 6.9 | 0.3592 | 19 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R/A110D, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R/A110D | Drosophila melanogaster | deoxycytidine | 3.5 | 0.584 | 5.993 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R/A110D, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R/A110D | Drosophila melanogaster | deoxyguanosine | 3.7 | 0.549 | 6.74 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R/A110D, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant M88R/A110D | Drosophila melanogaster | thymidine | 0.034 | 2.425 | 0.014 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant M88R/A110D, thymidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A | Drosophila melanogaster | 1-beta-D-arabinofuranosylcytosine | 2.53 | 0.0335 | 76 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A, 1-beta-D-arabinofuranosylcytosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A | Drosophila melanogaster | deoxyadenosine | 3.7 | — | — | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A | Drosophila melanogaster | deoxycytidine | 4.4 | 0.0025 | 1.76 × 10³ | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A | Drosophila melanogaster | deoxyguanosine | 2.8 | 0.1466 | 19 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A | Drosophila melanogaster | dideoxycytidine | 0.93 | 0.292 | 3.185 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A, dideoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A | Drosophila melanogaster | thymidine | 2.97 | 0.0113 | 260 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A, thymidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A/M88R/A110D | Drosophila melanogaster | deoxyadenosine | 3.5 | 0.153 | 23 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A/M88R/A110D, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A/M88R/A110D | Drosophila melanogaster | deoxycytidine | 1.94 | 0.627 | 2.615 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A/M88R/A110D, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A/M88R/A110D | Drosophila melanogaster | deoxyguanosine | 1.73 | — | — | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A/M88R/A110D, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84A/M88R/A110D | Drosophila melanogaster | thymidine | 0.11 | 1.512 | 0.072 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84A/M88R/A110D, thymidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84M | Drosophila melanogaster | deoxyadenosine | 1.36 | 0.8515 | 1.597 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84M, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84M | Drosophila melanogaster | deoxycytidine | 1.8 | 0.674 | 2.67 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84M, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84M | Drosophila melanogaster | deoxyguanosine | 0.22 | 1.911 | 0.115 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84M, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84M | Drosophila melanogaster | thymidine | 0.037 | 0.829 | 0.084 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84M, thymidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S | Drosophila melanogaster | deoxyadenosine | 1.1 | 0.1497 | 7.348 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S | Drosophila melanogaster | deoxycytidine | 0.83 | 0.0129 | 64 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S | Drosophila melanogaster | deoxyguanosine | 0.64 | 0.375 | 1.706 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S | Drosophila melanogaster | thymidine | 0.83 | 0.0247 | 33 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S, thymidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S/M88R/A110D | Drosophila melanogaster | deoxyadenosine | 3.2 | 0.388 | 8.247 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S/M88R/A110D, deoxyadenosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S/M88R/A110D | Drosophila melanogaster | deoxycytidine | 1.62 | 2.162 | 0.749 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S/M88R/A110D, deoxycytidine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S/M88R/A110D | Drosophila melanogaster | deoxyguanosine | 4.6 | 0.1592 | 29 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S/M88R/A110D, deoxyguanosine | |
| deoxyribonucleoside kinase (Dm-dNK)variant V84S/M88R/A110D | Drosophila melanogaster | thymidine | 0.23 | 6.56 | 0.035 | Open record: deoxyribonucleoside kinase (Dm-dNK) variant V84S/M88R/A110D, thymidine |