CatLogenzyme kinetics catalog

Values CatLog read from this paper

Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed…

PMID 20369883doi:10.1021/jp100668yOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 8 records (8 values) from this paper: microsomal prostaglandin E synthase-1 (mPGES-1) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 2.5.1.18, EC 5.3.99.3

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
microsomal prostaglandin E synthase-1 (mPGES-1)Homo sapiensprostaglandin H2—0.2155—pH 7.2Open
microsomal prostaglandin E synthase-1 (mPGES-1)variant N74AHomo sapiensprostaglandin H2—0.4643—pH 7.2Open
microsomal prostaglandin E synthase-1 (mPGES-1)variant R122AHomo sapiensprostaglandin H2—0.372—pH 7.2Open
microsomal prostaglandin E synthase-1 (mPGES-1)variant R70AHomo sapiensprostaglandin H2—0.296—pH 7.2Open
microsomal prostaglandin E synthase-1 (mPGES-1)variant R70A/R122AHomo sapiensprostaglandin H2—0.4737—pH 7.2Open
microsomal prostaglandin E synthase-1 (mPGES-1)variant T129VHomo sapiensprostaglandin H2—0.3842—pH 7.2Open
microsomal prostaglandin E synthase-1 (mPGES-1)variant Y117AHomo sapiensprostaglandin H2—0.5345—pH 7.2Open
microsomal prostaglandin E synthase-1 (mPGES-1)variant Y117SHomo sapiensprostaglandin H2—0.2832—pH 7.2Open