Values CatLog read from this paper
Identification of Allosteric Inhibitors against Active Caspase-6
PMID 30940883doi:10.1038/s41598-019-41930-7Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (30 values) from this paper: Caspase-6 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| Caspase-6 | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2.27 | 0.0312 | 76.01 | pH 7.2, 37 °C | Open record: Caspase-6, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6 | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2.6 | 0.0248 | 109.2 | pH 7.2, 37 °C | Open record: Caspase-6, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant A109T | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2.51 | 0.0345 | 72.68 | pH 7.2, 37 °C | Open record: Caspase-6 variant A109T, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant A34E | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2.04 | 0.0227 | 89.80 | pH 7.2, 37 °C | Open record: Caspase-6 variant A34E, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant E35K | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 1.71 | 0.0371 | 46.8 | pH 7.2, 37 °C | Open record: Caspase-6 variant E35K, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant K284A | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2 | 0.0326 | 58.65 | pH 7.2, 37 °C | Open record: Caspase-6 variant K284A, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant K284A | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2.8 | 0.0277 | 99.88 | pH 7.2, 37 °C | Open record: Caspase-6 variant K284A, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant L200A | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 0.05 | 0.3155 | 0.15 | pH 7.2, 37 °C | Open record: Caspase-6 variant L200A, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant L200A | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2.8 | 0.1962 | 15.15 | pH 7.2, 37 °C | Open record: Caspase-6 variant L200A, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |
| Caspase-6variant T182S | Homo sapiens | N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin | 2.42 | 0.0333 | 72.65 | pH 7.2, 37 °C | Open record: Caspase-6 variant T182S, N-acetyl-Val-Glu-Ile-Asp-7-amino-4-trifluoromethylcoumarin |