Values CatLog read from this paper

The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism

PMID 15769597doi:10.1016/j.bbapap.2005.01.006Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 24 records (72 values) from this paper: aldose reductase from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.21

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
aldose reductase	Homo sapiens	D-xylose	0.3	6	0.05	pH 7, 25 °C	Open record: aldose reductase, D-xylose
aldose reductase	Homo sapiens	DL-glyceraldehyde	0.5	0.02	27	pH 7, 25 °C	Open record: aldose reductase, DL-glyceraldehyde
aldose reductasevariant C298A	Homo sapiens	D-xylose	3.3	400	0.0083	pH 7, 25 °C	Open record: aldose reductase variant C298A, D-xylose
aldose reductasevariant C298A	Homo sapiens	DL-glyceraldehyde	4	0.6	6.8	pH 7, 25 °C	Open record: aldose reductase variant C298A, DL-glyceraldehyde
aldose reductasevariant G213P	Homo sapiens	D-xylose	7	5 × 10³	0.0014	pH 7, 25 °C	Open record: aldose reductase variant G213P, D-xylose
aldose reductasevariant G213P	Homo sapiens	DL-glyceraldehyde	4.6	3.7	1.3	pH 7, 25 °C	Open record: aldose reductase variant G213P, DL-glyceraldehyde
aldose reductasevariant G213S	Homo sapiens	D-xylose	2.4	260	0.0089	pH 7, 25 °C	Open record: aldose reductase variant G213S, D-xylose
aldose reductasevariant G213S	Homo sapiens	DL-glyceraldehyde	3.7	0.42	9	pH 7, 25 °C	Open record: aldose reductase variant G213S, DL-glyceraldehyde
aldose reductasevariant R268A	Homo sapiens	D-xylose	0.2	8	0.035	pH 7, 25 °C	Open record: aldose reductase variant R268A, D-xylose
aldose reductasevariant R268A	Homo sapiens	DL-glyceraldehyde	0.38	0.05	8.5	pH 7, 25 °C	Open record: aldose reductase variant R268A, DL-glyceraldehyde
aldose reductasevariant R293A	Homo sapiens	D-xylose	0.11	2.1	0.055	pH 7, 25 °C	Open record: aldose reductase variant R293A, D-xylose
aldose reductasevariant R293A	Homo sapiens	DL-glyceraldehyde	0.16	0.02	9	pH 7, 25 °C	Open record: aldose reductase variant R293A, DL-glyceraldehyde
aldose reductasevariant S210A	Homo sapiens	D-xylose	1.6	58	0.029	pH 7, 25 °C	Open record: aldose reductase variant S210A, D-xylose
aldose reductasevariant S210A	Homo sapiens	DL-glyceraldehyde	2	0.11	17	pH 7, 25 °C	Open record: aldose reductase variant S210A, DL-glyceraldehyde
aldose reductasevariant S214A	Homo sapiens	D-xylose	1.5	48	0.032	pH 7, 25 °C	Open record: aldose reductase variant S214A, D-xylose
aldose reductasevariant S214A	Homo sapiens	DL-glyceraldehyde	2.1	0.13	16	pH 7, 25 °C	Open record: aldose reductase variant S214A, DL-glyceraldehyde
aldose reductasevariant S226A	Homo sapiens	D-xylose	0.45	11	0.042	pH 7, 25 °C	Open record: aldose reductase variant S226A, D-xylose
aldose reductasevariant S226A	Homo sapiens	DL-glyceraldehyde	0.54	0.03	16	pH 7, 25 °C	Open record: aldose reductase variant S226A, DL-glyceraldehyde
aldose reductasevariant W219A	Homo sapiens	D-xylose	0.3	9.2	0.033	pH 7, 25 °C	Open record: aldose reductase variant W219A, D-xylose
aldose reductasevariant W219A	Homo sapiens	DL-glyceraldehyde	0.32	0.02	16	pH 7, 25 °C	Open record: aldose reductase variant W219A, DL-glyceraldehyde
aldose reductasevariant W219E	Homo sapiens	D-xylose	0.07	5.6	0.012	pH 7, 25 °C	Open record: aldose reductase variant W219E, D-xylose
aldose reductasevariant W219E	Homo sapiens	DL-glyceraldehyde	0.09	0.02	3.8	pH 7, 25 °C	Open record: aldose reductase variant W219E, DL-glyceraldehyde
aldose reductasevariant Δ214–219	Homo sapiens	D-xylose	1.48	270	0.0056	pH 7, 25 °C	Open record: aldose reductase variant Δ214–219, D-xylose
aldose reductasevariant Δ214–219	Homo sapiens	DL-glyceraldehyde	2.15	0.5	4.3	pH 7, 25 °C	Open record: aldose reductase variant Δ214–219, DL-glyceraldehyde