Values CatLog read from this paper
Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major
PMID 11420444doi:10.1110/ps.48801Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (17 values) from this paper: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) from Leishmania major.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxyadenosine 5'-triphosphate | 5.4 | 1.034 | 5.1 | pH 8, 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxyadenosine 5'-triphosphate |
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxycytidine 5'-triphosphate | 13 | — | 5 | pH 8, 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxycytidine 5'-triphosphate |
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxyguanosine 5'-triphosphate | 6.4 | — | 6.4 | pH 8, 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxyguanosine 5'-triphosphate |
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxythymidine 5'-triphosphate | 8.6 | 1.514 | 5.5 | pH 8, 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxythymidine 5'-triphosphate |
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxyuridine 5'-diphosphate | 65 | 0.0627 | 1 × 10³ | pH 8, 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxyuridine 5'-diphosphate |
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxyuridine 5'-triphosphatestopped-flow pH-indicator assay; 1 mg/ml BSA | — | 0.00211 | 2.3 × 10⁴ | pH 8, 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxyuridine 5'-triphosphate |
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxyuridine 5'-triphosphate0.5 mM cresol red; 25 mM BICINE | 49 | — | — | pH 8, 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxyuridine 5'-triphosphate |
| dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase) | Leishmania major | 2'-deoxyuridine 5'-triphosphate | — | 0.00235 | — | 25 °C | Open record: dUTPase (dUTP nucleotidohydrolase; dUTPase-dUDPase), 2'-deoxyuridine 5'-triphosphate |