Values CatLog read from this paper
Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo
PMID 19487291doi:10.1158/0008-5472.can-09-0615Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (24 values) from this paper: cytosine deaminase (bCD).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cytosine deaminase (bCD) | — | 5-fluorocytosine | 19.71 | 3.76 | 5.24 | Open record: cytosine deaminase (bCD), 5-fluorocytosine | |
| cytosine deaminase (bCD) | — | cytosine | 49.68 | 0.46 | 106.8 | Open record: cytosine deaminase (bCD), cytosine | |
| cytosine deaminase (bCD)variant D314E/F316L/D317G | — | 5-fluorocytosine | 83.68 | 6.73 | 12.44 | Open record: cytosine deaminase (bCD) variant D314E/F316L/D317G, 5-fluorocytosine | |
| cytosine deaminase (bCD)variant D314E/F316L/D317G | — | cytosine | 2.13 | 1.65 | 1.29 | Open record: cytosine deaminase (bCD) variant D314E/F316L/D317G, cytosine | |
| cytosine deaminase (bCD)variant V152A/F316C/D317G | — | 5-fluorocytosine | 101.7 | 12.69 | 8.02 | Open record: cytosine deaminase (bCD) variant V152A/F316C/D317G, 5-fluorocytosine | |
| cytosine deaminase (bCD)variant V152A/F316C/D317G | — | cytosine | 1.69 | 4.9 | 0.35 | Open record: cytosine deaminase (bCD) variant V152A/F316C/D317G, cytosine | |
| cytosine deaminase (bCD)variant V315L/F316V/D317G | — | 5-fluorocytosine | 115.2 | 7.55 | 15.27 | Open record: cytosine deaminase (bCD) variant V315L/F316V/D317G, 5-fluorocytosine | |
| cytosine deaminase (bCD)variant V315L/F316V/D317G | — | cytosine | 2.98 | 3.16 | 0.94 | Open record: cytosine deaminase (bCD) variant V315L/F316V/D317G, cytosine |