CatLogenzyme kinetics catalog

Values CatLog read from this paper

Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators

PMID 32324389doi:10.1021/acs.biochem.0c00233Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 7 records (21 values) from this paper: human platelet 12-lipoxygenase (h12-LOX), human reticulocyte 15-lipoxygenase-1 (h15-LOX-1) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.13.11.12, EC 1.13.11.31, EC 1.13.11.33

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
human platelet 12-lipoxygenase (h12-LOX)Homo sapiens14S-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid0.220.0882.4pH 8Open
human platelet 12-lipoxygenase (h12-LOX)Homo sapiens14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid0.170.210.8pH 8Open
human platelet 12-lipoxygenase (h12-LOX)Homo sapiensarachidonic acid189.5 × 10⁻⁴1.9 × 10⁴pH 8Open
human platelet 12-lipoxygenase (h12-LOX)Homo sapiensdocosahexaenoic acid139 × 10⁻⁴1.4 × 10⁴pH 8Open
human reticulocyte 15-lipoxygenase-1 (h15-LOX-1)Homo sapiens14S-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid20.018110pH 7.5Open
human reticulocyte 15-lipoxygenase-1 (h15-LOX-1)Homo sapiens14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid0.570.01830pH 7.5Open
human reticulocyte 15-lipoxygenase-1 (h15-LOX-1)Homo sapiensdocosahexaenoic acid2.40.0067360pH 7.5Open