Values CatLog read from this paper
Purification of the recombinant human serotonin N-acetyltransferase (EC 2.3.1.87): further characterization of and comparison with AANAT from other species
PMID 15477086doi:10.1016/j.pep.2004.07.004Open in Browse
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CatLog read 41 records (41 values) from this paper: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) from ovine, Homo sapiens, Rattus norvegicus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(2,4-Dichlorophenyl)-ethylamine | — | 0.34 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(2,4-Dichlorophenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(2-Chlorophenyl)-ethylamine | — | 2.74 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(2-Chlorophenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(3-Chlorophenyl)-ethylamine | — | 0.62 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(3-Chlorophenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(3-Fluorphenyl)-ethylamine | — | 1.1 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(3-Fluorphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(4-Bromphenyl)-ethylamine | — | 0.75 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(4-Bromphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(4-Fluorphenyl)-ethylamine | — | 2.22 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(4-Fluorphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(p-Fluorphenyl)-ethylamine | — | 0.98 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(p-Fluorphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-(p-Tolyl)-ethylamine | — | 1.17 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(p-Tolyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-Methoxyphenethylamine | — | 1.3 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-Methoxyphenethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-phenylethylamineGST fusion (pGEX-4T); expressed in E. coli BL21(DE3)pLysS | — | 0.17 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-phenylethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-Phenylethylamine | — | 0.17 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-Phenylethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 2-phenylethylamineV5- and hexahistidine-tagged | — | 1.5 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-phenylethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 5-hydroxytryptamineGST fusion (pGEX-4T); expressed in E. coli BL21(DE3)pLysS | — | 1.35 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 5-hydroxytryptamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 5-hydroxytryptamineV5- and hexahistidine-tagged | — | 5 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 5-hydroxytryptamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | 6-Hydroxydopamine | — | 1.9 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 6-Hydroxydopamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | acetyl coenzyme A | — | 0.53 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), acetyl coenzyme A |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | TryptamineGST fusion (pGEX-4T); expressed in E. coli BL21(DE3)pLysS | — | 0.88 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), Tryptamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Homo sapiens | TryptamineV5- and hexahistidine-tagged | — | 1.6 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), Tryptamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2,5-Dimethoxyphenethylamine | — | 0.47 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2,5-Dimethoxyphenethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(2,4-Dichlorophenyl)-ethylamine | — | 3.46 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(2,4-Dichlorophenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(2-Chlorophenyl)-ethylamine | — | 0.9 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(2-Chlorophenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(3,4-Dihydroxyphenyl)-ethylamine | — | 1.76 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(3,4-Dihydroxyphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(3-Chlorophenyl)-ethylamine | — | 1.31 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(3-Chlorophenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(3-Fluorphenyl)-ethylamine | — | 1.65 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(3-Fluorphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(4-Bromphenyl)-ethylamine | — | 1.55 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(4-Bromphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(4-Chlorophenyl)ethylamine | — | 2.33 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(4-Chlorophenyl)ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(4-Fluorphenyl)-ethylamine | — | 1.28 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(4-Fluorphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(p-Fluorphenyl)-ethylamine | — | 1.91 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(p-Fluorphenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(p-Nitrophenyl)-ethylamine | — | 1.405 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(p-Nitrophenyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-(p-Tolyl)-ethylamine | — | 1.58 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-(p-Tolyl)-ethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-Fluorphenethylamine | — | 1.37 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-Fluorphenethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-Methoxyphenethylamine | — | 0.49 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-Methoxyphenethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-phenylethylamine | — | 1.8 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-phenylethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 2-Phenylethylamine | — | 1.84 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-Phenylethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 3-Methoxy-2-phenylethylamine | — | 2.07 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 3-Methoxy-2-phenylethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 3-Methoxytyramine | — | 1.815 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 3-Methoxytyramine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | 5-hydroxytryptamine | — | 0.64 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 5-hydroxytryptamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | ovine | acetyl coenzyme A | — | 0.265 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), acetyl coenzyme A |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Rattus norvegicus | 2-phenylethylamine | — | 9.5 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 2-phenylethylamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Rattus norvegicus | 5-hydroxytryptamine | — | 1.7 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), 5-hydroxytryptamine |
| serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) | Rattus norvegicus | acetyl coenzyme A | — | 0.65 | — | pH 6.8, 37 °C | Open record: serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT), acetyl coenzyme A |