Values CatLog read from this paper
The facial triad in the α-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O2 activation
PMID 27815979doi:10.1016/j.jinorgbio.2016.10.007Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (18 values) from this paper: FIH (factor inhibiting hypoxia inducible factor-1α) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| FIH (factor inhibiting hypoxia inducible factor-1α) | Homo sapiens | 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN | 0.55 | 0.078 | 7 | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α), 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN |
| FIH (factor inhibiting hypoxia inducible factor-1α) | Homo sapiens | α-ketoglutarate | — | 0.02 | — | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α), α-ketoglutarate |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201E | Homo sapiens | 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN | 0.027 | 0.07 | 0.37 | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201E, 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201E | Homo sapiens | O2 | 0.0135 | 0.07 | 0.23 | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201E, O2 |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201E | Homo sapiens | α-ketoglutarate | — | 0.026 | — | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201E, α-ketoglutarate |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201G | Homo sapiens | 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN | 0.38 | 0.071 | 5.7 | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201G, 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201G | Homo sapiens | O2 | 0.33 | 0.115 | 3 | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201G, O2 |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201G | Homo sapiens | α-ketoglutarate | — | 0.023 | — | pH 7, 37 °C | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201G, α-ketoglutarate |