EC 1.14.11.n4
OxidoreductasesOpen in Browse
CatLog read 8 records for EC 1.14.11.n4 from 1 paper, for 1 organism. Names in these papers: FIH (factor inhibiting hypoxia inducible factor-1α).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The facial triad in the α-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O2 activation | Homo sapiens | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| FIH (factor inhibiting hypoxia inducible factor-1α) | Homo sapiens | 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN | 0.55 | 0.078 | 7 | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α), 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN |
| FIH (factor inhibiting hypoxia inducible factor-1α) | Homo sapiens | α-ketoglutarate | — | 0.02 | — | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α), α-ketoglutarate |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201E | Homo sapiens | 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN | 0.027 | 0.07 | 0.37 | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201E, 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201E | Homo sapiens | O2 | 0.0135 | 0.07 | 0.23 | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201E, O2 |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201E | Homo sapiens | α-ketoglutarate | — | 0.026 | — | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201E, α-ketoglutarate |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201G | Homo sapiens | 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN | 0.38 | 0.071 | 5.7 | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201G, 39-residue CTAD peptide of human HIF-1α (HIF-1α 788-826, Cys800Ala): DESGLPQLTSYDAEVNAPIQGSRNLLQGEELLRALDQVN |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201G | Homo sapiens | O2 | 0.33 | 0.115 | 3 | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201G, O2 |
| FIH (factor inhibiting hypoxia inducible factor-1α)variant D201G | Homo sapiens | α-ketoglutarate | — | 0.023 | — | pH 7, 37 °C | PMID 27815979 | Open record: FIH (factor inhibiting hypoxia inducible factor-1α) variant D201G, α-ketoglutarate |