CatLogenzyme kinetics catalog

Values CatLog read from this paper

Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines

PMID 15078100doi:10.1021/bi035923wOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 15 records (21 values) from this paper: quinone oxidoreductase 2 (QR2) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 1.10.5.1

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
quinone oxidoreductase 2 (QR2)Homo sapiensmenadionesimple Michaelis-Menten fit; cosubstrate NMeH (100 µM)2760.00416.7 × 10⁴ calc.pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensmenadionesimple Michaelis-Menten fit; cosubstrate NMeH (100 µM)1890.00355.4 × 10⁴ calc.pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensmenadionecosubstrate NMeH; expressed in E. coli BL-21 as GST fusion—0.0094—pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensmenadionecosubstrate NMeH; Table 2—0.0116—pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensmenadioneinhibition series with 0; 4; 10; cosubstrate NMeH (60 µM)—0.01—pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensmenadioneinhibition series with 0; 4; 10; 20 µM primaquine (Figure 5)—0.011—pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensmenadioneinhibition series with 0; 0.5; 2; 5 µM quinacrine (Figure 5)—0.018—pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamidesimple Michaelis-Menten fit; cosubstrate menadione (40 µM)2150.0415.2 × 10³ calc.pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamidesimple Michaelis-Menten fit; cosubstrate menadione (40 µM)2010.0171.2 × 10⁴ calc.pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamidecosubstrate menadione; GST removed by thrombin cleavage4620.01792.58 × 10⁴ calc.pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamidecosubstrate menadione; Table 28580.03032.83 × 10⁴ calc.pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamide98——pH 8.5, 4 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamideinhibition series with 0; 4; 10; Table 3—0.023—pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamideinhibition series with 0; 4; 10; 20 µM primaquine (Figure 5)—0.013—pH 8.5, 25 °COpen
quinone oxidoreductase 2 (QR2)Homo sapiensN-methyldihydronicotinamideinhibition series with 0; 0.5; 2; 5 µM quinacrine (Figure 5)—0.02—pH 8.5, 25 °COpen