Values CatLog read from this paper
Kinetic mechanism of AKT/PKB enzyme family
PMID 16540465doi:10.1074/jbc.m601384200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (15 values) from this paper: AKT1 (PKBalpha), AKT2 (PKBbeta), AKT3 (PKBgamma).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 3 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AKT1 (PKBalpha) | — | adenosine 5'-triphosphatesequential mechanism fit; purified enzyme activated in vitro | 0.37 | 0.0528 | 6.9 calc. | pH 7.4 | Open record: AKT1 (PKBalpha), adenosine 5'-triphosphate |
| AKT1 (PKBalpha) | — | adenosine 5'-triphosphate | — | 0.1433 | — | pH 7.4 | Open record: AKT1 (PKBalpha), adenosine 5'-triphosphate |
| AKT1 (PKBalpha) | — | ARKRERTYSFGHHAsequential mechanism fit; purified enzyme activated in vitro | — | 5 × 10⁻⁴ | — | pH 7.4 | Open record: AKT1 (PKBalpha), ARKRERTYSFGHHA |
| AKT1 (PKBalpha) | — | ARKRERTYSFGHHA | — | 0.0029 | — | pH 7.4 | Open record: AKT1 (PKBalpha), ARKRERTYSFGHHA |
| AKT2 (PKBbeta) | — | adenosine 5'-triphosphatesequential mechanism fit; purified enzyme activated in vitro | 0.42 | 0.3584 | 1.2 calc. | pH 7.4 | Open record: AKT2 (PKBbeta), adenosine 5'-triphosphate |
| AKT2 (PKBbeta) | — | adenosine 5'-triphosphate | — | 0.564 | — | pH 7.4 | Open record: AKT2 (PKBbeta), adenosine 5'-triphosphate |
| AKT2 (PKBbeta) | — | ARKRERTYSFGHHAsequential mechanism fit; purified enzyme activated in vitro | — | 0.0034 | — | pH 7.4 | Open record: AKT2 (PKBbeta), ARKRERTYSFGHHA |
| AKT2 (PKBbeta) | — | ARKRERTYSFGHHA | — | 0.0023 | — | pH 7.4 | Open record: AKT2 (PKBbeta), ARKRERTYSFGHHA |
| AKT3 (PKBgamma) | — | adenosine 5'-triphosphatesequential mechanism fit; purified enzyme activated in vitro | 1.98 | 0.0879 | 22.6 calc. | pH 7.4 | Open record: AKT3 (PKBgamma), adenosine 5'-triphosphate |
| AKT3 (PKBgamma) | — | adenosine 5'-triphosphate | — | 0.1187 | — | pH 7.4 | Open record: AKT3 (PKBgamma), adenosine 5'-triphosphate |
| AKT3 (PKBgamma) | — | ARKRERTYSFGHHAsequential mechanism fit; purified enzyme activated in vitro | — | 0.0124 | — | pH 7.4 | Open record: AKT3 (PKBgamma), ARKRERTYSFGHHA |
| AKT3 (PKBgamma) | — | ARKRERTYSFGHHA | — | 0.0023 | — | pH 7.4 | Open record: AKT3 (PKBgamma), ARKRERTYSFGHHA |