Values CatLog read from this paper
Insight into the structural flexibility and function of Mycobacterium tuberculosis isocitrate lyase
PMID 25576828doi:10.1016/j.biochi.2014.12.016Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 4 records (8 values) from this paper: isocitrate lyase (MtbICL) from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| isocitrate lyase (MtbICL) | Mycobacterium tuberculosis | threo-DL-isocitrate | 9.78 | 1.142 | 8.56 calc. | pH 7.5, 30 °C | Open record: isocitrate lyase (MtbICL), threo-DL-isocitrate |
| isocitrate lyase (MtbICL)variant E423D | Mycobacterium tuberculosis | threo-DL-isocitrate | 8.34 | 1.423 | 5.86 calc. | pH 7.5, 30 °C | Open record: isocitrate lyase (MtbICL) variant E423D, threo-DL-isocitrate |
| isocitrate lyase (MtbICL)variant E423D/E424D | Mycobacterium tuberculosis | threo-DL-isocitrate | 7.53 | 2.031 | 3.71 calc. | pH 7.5, 30 °C | Open record: isocitrate lyase (MtbICL) variant E423D/E424D, threo-DL-isocitrate |
| isocitrate lyase (MtbICL)variant E424D | Mycobacterium tuberculosis | threo-DL-isocitrate | 8.46 | 1.861 | 4.55 calc. | pH 7.5, 30 °C | Open record: isocitrate lyase (MtbICL) variant E424D, threo-DL-isocitrate |