Values CatLog read from this paper
Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation
PMID 15576032doi:10.1016/j.str.2004.09.013Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (30 values) from this paper: branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b), branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b) | Homo sapiens | α-ketoisovalerate | 0.2 | 0.05 | 4 | Open record: branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b), α-ketoisovalerate | |
| branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b)variant S292-α-PO3 (S302A background, Ser292-α phosphorylated) | Homo sapiens | α-ketoisovalerate | 0.15 | 0.983 | 0.15 | Open record: branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b) variant S292-α-PO3 (S302A background, Ser292-α phosphorylated), α-ketoisovalerate | |
| branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b)variant S292D/S302A | Homo sapiens | α-ketoisovalerate | 1.65 | 4.896 | 0.33 | Open record: branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b) variant S292D/S302A, α-ketoisovalerate | |
| branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b)variant S292E/S302A | Homo sapiens | α-ketoisovalerate | 0.128 | 0.593 | 0.22 | Open record: branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b) variant S292E/S302A, α-ketoisovalerate | |
| branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b)variant S292N/S302A | Homo sapiens | α-ketoisovalerate | 2.77 | 0.224 | 12.3 | Open record: branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b) variant S292N/S302A, α-ketoisovalerate | |
| branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b)variant S302A | Homo sapiens | α-ketoisovalerate | 0.62 | 0.022 | 28 | Open record: branched-chain α-ketoacid decarboxylase/dehydrogenase (E1b) variant S302A, α-ketoisovalerate | |
| branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3 | Homo sapiens | α-ketoisovalerate | 3.3 | 0.048 | 67 | Open record: branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3, α-ketoisovalerate | |
| branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3variant S292D/S302A | Homo sapiens | α-ketoisovalerate | 0.58 | 4.381 | 0.132 | Open record: branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3 variant S292D/S302A, α-ketoisovalerate | |
| branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3variant S292N/S302A | Homo sapiens | α-ketoisovalerate | 3.92 | 0.193 | 20.2 | Open record: branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3 variant S292N/S302A, α-ketoisovalerate | |
| branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3variant S302A | Homo sapiens | α-ketoisovalerate | 2.18 | 0.028 | 77 | Open record: branched-chain α-ketoacid dehydrogenase complex (BCKDC) reconstituted with E1b, lipoylated E2b and E3 variant S302A, α-ketoisovalerate |