Values CatLog read from this paper
Characterization of the active-site residues asparagine 167 and lysine 161 of the IMP-1 metallo beta-lactamase
PMID 11287151doi:10.1111/j.1574-6968.2001.tb10587.xOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 30 records (72 values) from this paper: IMP-1 metallo-beta-lactamase from Klebsiella pneumoniae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| IMP-1 metallo-beta-lactamase | Klebsiella pneumoniae | Benzylpenicillin | 212 | 0.28 | 760 | pH 7 | Open record: IMP-1 metallo-beta-lactamase, Benzylpenicillin |
| IMP-1 metallo-beta-lactamase | Klebsiella pneumoniae | Cefoxitin | 12.7 | 0.0016 | 8 × 10³ | pH 7 | Open record: IMP-1 metallo-beta-lactamase, Cefoxitin |
| IMP-1 metallo-beta-lactamase | Klebsiella pneumoniae | Cefuroxime | 58 | 8.3 × 10⁻⁴ | 7 × 10⁴ | pH 7 | Open record: IMP-1 metallo-beta-lactamase, Cefuroxime |
| IMP-1 metallo-beta-lactamase | Klebsiella pneumoniae | Cephalothin | 35 | 0.0026 | 1.4 × 10⁴ | pH 7 | Open record: IMP-1 metallo-beta-lactamase, Cephalothin |
| IMP-1 metallo-beta-lactamase | Klebsiella pneumoniae | Imipenem | 41 | 0.019 | 2.2 × 10³ | pH 7 | Open record: IMP-1 metallo-beta-lactamase, Imipenem |
| IMP-1 metallo-beta-lactamasevariant K161A | Klebsiella pneumoniae | Benzylpenicillin | — | — | 1 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161A, Benzylpenicillin |
| IMP-1 metallo-beta-lactamasevariant K161A | Klebsiella pneumoniae | Cefoxitin | 9 | 0.8 | 11 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161A, Cefoxitin |
| IMP-1 metallo-beta-lactamasevariant K161A | Klebsiella pneumoniae | Cefuroxime | 180 | 0.47 | 380 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161A, Cefuroxime |
| IMP-1 metallo-beta-lactamasevariant K161A | Klebsiella pneumoniae | Cephalothin | 290 | 0.7 | 420 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161A, Cephalothin |
| IMP-1 metallo-beta-lactamasevariant K161A | Klebsiella pneumoniae | Imipenem | — | — | 7.7 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161A, Imipenem |
| IMP-1 metallo-beta-lactamasevariant K161E | Klebsiella pneumoniae | Benzylpenicillin | — | — | 0.3 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161E, Benzylpenicillin |
| IMP-1 metallo-beta-lactamasevariant K161E | Klebsiella pneumoniae | Cefoxitin | 1.3 | 1.1 | 3 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161E, Cefoxitin |
| IMP-1 metallo-beta-lactamasevariant K161E | Klebsiella pneumoniae | Cefuroxime | — | — | 31 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161E, Cefuroxime |
| IMP-1 metallo-beta-lactamasevariant K161E | Klebsiella pneumoniae | Cephalothin | 90 | 1.2 | 38 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161E, Cephalothin |
| IMP-1 metallo-beta-lactamasevariant K161E | Klebsiella pneumoniae | Imipenem | — | — | 4.5 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161E, Imipenem |
| IMP-1 metallo-beta-lactamasevariant K161R | Klebsiella pneumoniae | Benzylpenicillin | 1.1 | 0.1 | 11 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161R, Benzylpenicillin |
| IMP-1 metallo-beta-lactamasevariant K161R | Klebsiella pneumoniae | Cefoxitin | 28 | 0.48 | 570 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161R, Cefoxitin |
| IMP-1 metallo-beta-lactamasevariant K161R | Klebsiella pneumoniae | Cefuroxime | 26 | 0.006 | 4.3 × 10³ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161R, Cefuroxime |
| IMP-1 metallo-beta-lactamasevariant K161R | Klebsiella pneumoniae | Cephalothin | 53 | 0.013 | 4 × 10³ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161R, Cephalothin |
| IMP-1 metallo-beta-lactamasevariant K161R | Klebsiella pneumoniae | Imipenem | — | — | 1.3 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant K161R, Imipenem |
| IMP-1 metallo-beta-lactamasevariant N167A | Klebsiella pneumoniae | Benzylpenicillin | 800 | 0.58 | 1.4 × 10³ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167A, Benzylpenicillin |
| IMP-1 metallo-beta-lactamasevariant N167A | Klebsiella pneumoniae | Cefoxitin | 90 | 0.033 | 2.7 × 10³ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167A, Cefoxitin |
| IMP-1 metallo-beta-lactamasevariant N167A | Klebsiella pneumoniae | Cefuroxime | 190 | 0.015 | 1.3 × 10⁴ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167A, Cefuroxime |
| IMP-1 metallo-beta-lactamasevariant N167A | Klebsiella pneumoniae | Cephalothin | 230 | 0.015 | 1.6 × 10⁴ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167A, Cephalothin |
| IMP-1 metallo-beta-lactamasevariant N167A | Klebsiella pneumoniae | Imipenem | — | — | 340 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167A, Imipenem |
| IMP-1 metallo-beta-lactamasevariant N167D | Klebsiella pneumoniae | Benzylpenicillin | — | — | 350 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167D, Benzylpenicillin |
| IMP-1 metallo-beta-lactamasevariant N167D | Klebsiella pneumoniae | Cefoxitin | 38 | 0.077 | 500 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167D, Cefoxitin |
| IMP-1 metallo-beta-lactamasevariant N167D | Klebsiella pneumoniae | Cefuroxime | 120 | 0.019 | 6.3 × 10³ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167D, Cefuroxime |
| IMP-1 metallo-beta-lactamasevariant N167D | Klebsiella pneumoniae | Cephalothin | 170 | 0.0098 | 1.8 × 10⁴ | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167D, Cephalothin |
| IMP-1 metallo-beta-lactamasevariant N167D | Klebsiella pneumoniae | Imipenem | — | — | 160 | pH 7 | Open record: IMP-1 metallo-beta-lactamase variant N167D, Imipenem |