Values CatLog read from this paper

Mutant N143P reveals how Na+ activates thrombin

PMID 19846563doi:10.1074/jbc.m109.069500Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 23 records (47 values) from this paper: thrombin from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.4.21.5

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
thrombin	Homo sapiens	fibrinogen	—	—	1.7 × 10⁴	pH 7.4, 37 °C	Open record: thrombin, fibrinogen
thrombin	Homo sapiens	H-D-Phe-Gly-Arg-p-nitroanilide	—	—	520	pH 7.4, 37 °C	Open record: thrombin, H-D-Phe-Gly-Arg-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Arg-p-nitroanilide200 mM ChCl (Na+-free)	3.5	8.8 × 10⁻⁴	4 × 10³	pH 8, 25 °C	Open record: thrombin, H-D-Phe-Pro-Arg-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Arg-p-nitroanilide200 mM NaCl (Na+-bound)	29	3.3 × 10⁻⁴	8.8 × 10⁴	pH 8, 25 °C	Open record: thrombin, H-D-Phe-Pro-Arg-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Arg-p-nitroanilide	—	—	3.7 × 10⁴	pH 7.4, 37 °C	Open record: thrombin, H-D-Phe-Pro-Arg-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Arg-p-nitroanilidewith 100 nM thrombomodulin and 5 mM CaCl2	—	—	3.4 × 10⁴	pH 7.4, 37 °C	Open record: thrombin, H-D-Phe-Pro-Arg-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Lys-p-nitroanilide200 mM ChCl (Na+-free)	12	0.04	300	pH 8, 25 °C	Open record: thrombin, H-D-Phe-Pro-Lys-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Lys-p-nitroanilide200 mM NaCl (Na+-bound)	28	0.004	7 × 10³	pH 8, 25 °C	Open record: thrombin, H-D-Phe-Pro-Lys-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Lys-p-nitroanilide	—	—	4.2 × 10³	pH 7.4, 37 °C	Open record: thrombin, H-D-Phe-Pro-Lys-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Phe-p-nitroanilide200 mM ChCl (Na+-free)	1.4	0.11	13	pH 8, 25 °C	Open record: thrombin, H-D-Phe-Pro-Phe-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Phe-p-nitroanilide200 mM NaCl (Na+-bound)	8.3	0.017	480	pH 8, 25 °C	Open record: thrombin, H-D-Phe-Pro-Phe-p-nitroanilide
thrombin	Homo sapiens	H-D-Phe-Pro-Phe-p-nitroanilide	—	—	280	pH 7.4, 37 °C	Open record: thrombin, H-D-Phe-Pro-Phe-p-nitroanilide
thrombin	Homo sapiens	protease-activated receptor 1	—	—	3.9 × 10⁴	pH 7.4, 37 °C	Open record: thrombin, protease-activated receptor 1
thrombin	Homo sapiens	protease-activated receptor 3	—	—	350	pH 7.4, 37 °C	Open record: thrombin, protease-activated receptor 3
thrombin	Homo sapiens	protease-activated receptor 4	—	—	340	pH 7.4, 37 °C	Open record: thrombin, protease-activated receptor 4
thrombin	Homo sapiens	protein Cactivation of protein C; no thrombomodulin	—	—	0.059	pH 7.4, 37 °C	Open record: thrombin, protein C
thrombin	Homo sapiens	protein C	—	—	220	pH 7.4, 37 °C	Open record: thrombin, protein C
thrombinvariant N143P	Homo sapiens	H-D-Phe-Pro-Arg-p-nitroanilide200 mM ChCl (Na+-free)	7.5	0.013	560	pH 8, 25 °C	Open record: thrombin variant N143P, H-D-Phe-Pro-Arg-p-nitroanilide
thrombinvariant N143P	Homo sapiens	H-D-Phe-Pro-Arg-p-nitroanilide200 mM NaCl (Na+-bound)	6	0.0029	2.1 × 10³	pH 8, 25 °C	Open record: thrombin variant N143P, H-D-Phe-Pro-Arg-p-nitroanilide
thrombinvariant N143P	Homo sapiens	H-D-Phe-Pro-Lys-p-nitroanilide200 mM ChCl (Na+-free)	0.26	0.072	3.6	pH 8, 25 °C	Open record: thrombin variant N143P, H-D-Phe-Pro-Lys-p-nitroanilide
thrombinvariant N143P	Homo sapiens	H-D-Phe-Pro-Lys-p-nitroanilide200 mM NaCl (Na+-bound)	0.18	0.0064	28	pH 8, 25 °C	Open record: thrombin variant N143P, H-D-Phe-Pro-Lys-p-nitroanilide
thrombinvariant N143P	Homo sapiens	H-D-Phe-Pro-Phe-p-nitroanilide200 mM ChCl (Na+-free)	0.23	0.04	5.8	pH 8, 25 °C	Open record: thrombin variant N143P, H-D-Phe-Pro-Phe-p-nitroanilide
thrombinvariant N143P	Homo sapiens	H-D-Phe-Pro-Phe-p-nitroanilide200 mM NaCl (Na+-bound)	0.18	0.033	5.4	pH 8, 25 °C	Open record: thrombin variant N143P, H-D-Phe-Pro-Phe-p-nitroanilide