CatLogenzyme kinetics catalog

Values CatLog read from this paper

Crystallographic evidence for a domain motion in rat nucleoside triphosphate diphosphohydrolase (NTPDase) 1

PMID 22100451doi:10.1016/j.jmb.2011.10.050Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 26 records (52 values) from this paper: NTPDase1 (CD39) from Rattus norvegicus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.6.1.5

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
NTPDase1 (CD39)Rattus norvegicusadenosine 5'-diphosphate77.30.00471.64 × 10⁴pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusadenosine 5′-[(α,β)-methyleno] triphosphate40.5——pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphate—0.0114—pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphate83.2——pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphate——7.3 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM AMP (inhibitor); apparent Km—0.0488—pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM AMP (inhibitor); apparent kcat82.6——pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM AMP (inhibitor); apparent kcat/Km——1.7 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM UMP (inhibitor); apparent Km—0.0131—pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM UMP (inhibitor); apparent kcat83.2——pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM UMP (inhibitor); apparent kcat/Km——6.4 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM AHM (inhibitor); apparent Km—0.149—pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM AHM (inhibitor); apparent kcat103.7——pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-diphosphatein presence of 100 μM AHM (inhibitor); apparent kcat/Km——700pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusguanosine 5'-triphosphate80.90.0099 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusinosine 5'-diphosphate79.90.01057.6 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusinosine 5'-triphosphate105.30.01089.8 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusthiamine pyrophosphate80.20.7495110pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusuridine 5'-diphosphate80.90.01137.2 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)Rattus norvegicusuridine 5'-triphosphate103.40.011.03 × 10⁴pH 7.4, 25 °COpen
NTPDase1 (CD39)variant K257MRattus norvegicusadenosine 5'-diphosphate50.40.00252.02 × 10⁴pH 7.4, 25 °COpen
NTPDase1 (CD39)variant Y409FRattus norvegicusadenosine 5'-diphosphate31.10.00516.1 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)variant Y413FRattus norvegicusadenosine 5'-diphosphate86.10.00322.69 × 10⁴pH 7.4, 25 °COpen
NTPDase1 (CD39)variant ΔMIL (T190–A206 replaced by KTPGGS)Rattus norvegicusadenosine 5'-diphosphate86.90.00591.47 × 10⁴pH 7.4, 25 °COpen
NTPDase1 (CD39)variant ΔMIL (T190–A206 replaced by KTPGGS)Rattus norvegicusuridine 5'-diphosphate930.01755.3 × 10³pH 7.4, 25 °COpen
NTPDase1 (CD39)variant ΔMIL (T190–A206 replaced by KTPGGS)Rattus norvegicusuridine 5'-triphosphate121.20.01299.4 × 10³pH 7.4, 25 °COpen