CatLogenzyme kinetics catalog

Values CatLog read from this paper

Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1

PMID 35469921doi:10.1016/j.jbc.2022.101974Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 48 records (48 values) from this paper: Oct1, OCT1 from Mus musculus, Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
OCT1Homo sapiens1-methyl-4-phenylpyridinium—0.0711—pH 7.4, 37 °COpen
OCT1Homo sapiens4-(4-(dimethylamino)styryl)-N-methylpyridinium—0.063—pH 7.4, 37 °COpen
OCT1Homo sapiensAdrenaline—0.558—pH 7.4, 37 °COpen
OCT1Homo sapiensDopamine—0.674—pH 7.4, 37 °COpen
OCT1Homo sapiensFenoterol—8.7 × 10⁻⁴—pH 7.4, 37 °COpen
OCT1Homo sapiensFormoterol—0.0132—pH 7.4, 37 °COpen
OCT1Homo sapiensHistamine—4.675—pH 7.4, 37 °COpen
OCT1Homo sapiensIpratropium—0.0107—pH 7.4, 37 °COpen
OCT1Homo sapiensMethylnaltrexone—0.01—pH 7.4, 37 °COpen
OCT1Homo sapiensOrciprenaline—0.53—pH 7.4, 37 °COpen
OCT1Homo sapiensPhenformin—0.0187—pH 7.4, 37 °COpen
OCT1Homo sapiensPirbuterol—0.0292—pH 7.4, 37 °COpen
OCT1Homo sapiensRactopamine—0.00217—pH 7.4, 37 °COpen
OCT1Homo sapiensRanitidine—0.0557—pH 7.4, 37 °COpen
OCT1Homo sapiensRitodrine—6.8 × 10⁻⁴—pH 7.4, 37 °COpen
OCT1Homo sapiensSalbutamol—0.395—pH 7.4, 37 °COpen
OCT1Homo sapiensSerotonin—0.663—pH 7.4, 37 °COpen
OCT1Homo sapiensSumatriptan—0.0659—pH 7.4, 37 °COpen
OCT1Homo sapiensTerbutaline—0.197—pH 7.4, 37 °COpen
OCT1Homo sapienstetraethylammonium—0.749—pH 7.4, 37 °COpen
OCT1Homo sapienstetrapropylammonium—0.0114—pH 7.4, 37 °COpen
OCT1Homo sapiensTiotropium—0.00782—pH 7.4, 37 °COpen
OCT1Homo sapiensTrospium—0.017—pH 7.4, 37 °COpen
Oct1Mus musculus1-methyl-4-phenylpyridinium—0.0244—pH 7.4, 37 °COpen
Oct1Mus musculus4-(4-(dimethylamino)styryl)-N-methylpyridinium—0.0128—pH 7.4, 37 °COpen
Oct1Mus musculusAdrenaline—0.242—pH 7.4, 37 °COpen
Oct1Mus musculusCholine—1.286—pH 7.4, 37 °COpen
Oct1Mus musculusDopamine—0.285—pH 7.4, 37 °COpen
Oct1Mus musculusFenoterol—0.0069—pH 7.4, 37 °COpen
Oct1Mus musculusFormoterol—0.00981—pH 7.4, 37 °COpen
Oct1Mus musculusHistamine—0.497—pH 7.4, 37 °COpen
Oct1Mus musculusIpratropium—0.00606—pH 7.4, 37 °COpen
Oct1Mus musculusMethylnaltrexone—0.00861—pH 7.4, 37 °COpen
Oct1Mus musculusNoradrenaline—0.409—pH 7.4, 37 °COpen
Oct1Mus musculusOrciprenaline—0.0898—pH 7.4, 37 °COpen
Oct1Mus musculusPhenformin—0.00753—pH 7.4, 37 °COpen
Oct1Mus musculusPirbuterol—0.0265—pH 7.4, 37 °COpen
Oct1Mus musculusRactopamine—0.00254—pH 7.4, 37 °COpen
Oct1Mus musculusRanitidine—0.0844—pH 7.4, 37 °COpen
Oct1Mus musculusRitodrine—0.00634—pH 7.4, 37 °COpen
Oct1Mus musculusSalbutamol—0.0522—pH 7.4, 37 °COpen
Oct1Mus musculusSerotonin—0.257—pH 7.4, 37 °COpen
Oct1Mus musculusSumatriptan—0.0657—pH 7.4, 37 °COpen
Oct1Mus musculusTerbutaline—0.0604—pH 7.4, 37 °COpen
Oct1Mus musculustetraethylammonium—0.305—pH 7.4, 37 °COpen
Oct1Mus musculustetrapropylammonium—0.00397—pH 7.4, 37 °COpen
Oct1Mus musculusTiotropium—0.00147—pH 7.4, 37 °COpen
Oct1Mus musculusTrospium—0.00181—pH 7.4, 37 °COpen