Values CatLog read from this paper
Differential regulation of SIRT5 activity by reduced nicotinic acid riboside (NARH)
PMID 41409579doi:10.1039/d5cb00191aOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (14 values) from this paper: SIRT5 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| SIRT5 | Homo sapiens | histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) | 0.029 | 0.0757 | 0.38 calc. | pH 7.5, 37 °C | Open record: SIRT5, histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) |
| SIRT5 | Homo sapiens | p53 peptide KKGQSTSRHK(K-Ac)LMFKTEG (acetylated Lys382)Table 1 | 0.0187 | 1.058 | 0.0177 calc. | pH 7.5, 37 °C | Open record: SIRT5, p53 peptide KKGQSTSRHK(K-Ac)LMFKTEG (acetylated Lys382) |
| SIRT5 | Homo sapiens | p53 peptide KKGQSTSRHK(K-Ac)LMFKTEG (acetylated Lys382)in the text | — | — | 0.0177 | pH 7.5, 37 °C | Open record: SIRT5, p53 peptide KKGQSTSRHK(K-Ac)LMFKTEG (acetylated Lys382) |
| SIRT5 | Homo sapiens | p53 peptide KKGQSTSRHK(K-Ac)LMFKTEG (acetylated Lys382)with 800 µM NARH (effector); in the text | — | — | 0.0129 | pH 7.5, 37 °C | Open record: SIRT5, p53 peptide KKGQSTSRHK(K-Ac)LMFKTEG (acetylated Lys382) |
| SIRT5variant A86S | Homo sapiens | histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) | 0.0673 | 0.139 | 0.484 calc. | pH 7.5, 37 °C | Open record: SIRT5 variant A86S, histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) |
| SIRT5variant R105A | Homo sapiens | histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) | 0.0074 | 0.616 | 0.012 calc. | pH 7.5, 37 °C | Open record: SIRT5 variant R105A, histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) |
| SIRT5variant W222A | Homo sapiens | histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) | 0.025 | 0.193 | 0.13 calc. | pH 7.5, 37 °C | Open record: SIRT5 variant W222A, histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) |
| SIRT5variant Y102A | Homo sapiens | histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) | 0.0371 | 1.23 | 0.0302 calc. | pH 7.5, 37 °C | Open record: SIRT5 variant Y102A, histone H3 peptide ARTKQTAR(K-Suc)STGGKAPRKQLAS (succinylated Lys9) |