Values CatLog read from this paper
Control activity of yeast geranylgeranyl diphosphate synthase from dimer interface through H-bonds and hydrophobic interaction
PMID 23534508doi:10.1021/bi4001276Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 22 records (33 values) from this paper: geranylgeranyl diphosphate synthase (GGPPS) from Saccharomyces cerevisiae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 11 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
EC 2.5.1.1, EC 2.5.1.10, EC 2.5.1.29
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| geranylgeranyl diphosphate synthase (GGPPS) | Saccharomyces cerevisiae | farnesyl diphosphate | 0.037 | 0.0037 | 10 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS), farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS) | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0017 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS), isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant M111A | Saccharomyces cerevisiae | farnesyl diphosphate | 0.04 | 0.0037 | 11 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant M111A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant M111A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0025 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant M111A, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant M111E | Saccharomyces cerevisiae | farnesyl diphosphate | 0.02 | 0.009 | 2.2 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant M111E, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant M111E | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0066 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant M111E, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant M111F | Saccharomyces cerevisiae | farnesyl diphosphate | 0.036 | 0.0146 | 2.5 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant M111F, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant M111F | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0113 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant M111F, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N101A | Saccharomyces cerevisiae | farnesyl diphosphate | 0.067 | 0.0063 | 11 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N101A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N101A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0048 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N101A, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N101A/N104A | Saccharomyces cerevisiae | farnesyl diphosphate | 2 × 10⁻⁴ | 0.0153 | 0.013 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N101A/N104A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N101A/N104A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0292 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N101A/N104A, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N101A/Y105A | Saccharomyces cerevisiae | farnesyl diphosphate | 1.3 × 10⁻⁴ | 0.0061 | 0.021 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N101A/Y105A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N101A/Y105A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0061 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N101A/Y105A, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N104A | Saccharomyces cerevisiae | farnesyl diphosphate | 0.11 | 0.0055 | 20 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N104A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N104A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0055 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N104A, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N104A/Y105A | Saccharomyces cerevisiae | farnesyl diphosphate | 0.017 | 0.0467 | 0.36 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N104A/Y105A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant N104A/Y105A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0081 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant N104A/Y105A, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant R140A | Saccharomyces cerevisiae | farnesyl diphosphate | 0.038 | 0.0089 | 4.3 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant R140A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant R140A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0045 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant R140A, isopentenyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant Y105A | Saccharomyces cerevisiae | farnesyl diphosphate | 0.06 | 0.0077 | 7.8 calc. | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant Y105A, farnesyl diphosphate |
| geranylgeranyl diphosphate synthase (GGPPS)variant Y105A | Saccharomyces cerevisiae | isopentenyl diphosphate | — | 0.0026 | — | pH 7.5, 25 °C | Open record: geranylgeranyl diphosphate synthase (GGPPS) variant Y105A, isopentenyl diphosphate |