Values CatLog read from this paper
Comparative enzymology of 11 beta -hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (Guinea pig) versus sensitive (human) species
PMID 12397058doi:10.1074/jbc.m210135200Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (18 values) from this paper: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) from Cavia porcellus, Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Cavia porcellus | cortisol | 0.035 | 0.0031 | 10.5 | pH 9.2, 37 °C | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisol |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Cavia porcellus | cortisone | — | 0.0022 | — | pH 7.4, 37 °C | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Cavia porcellus | cortisone1-3 h incubation with cortisone plus 3H-labeled tracer | — | 2.8 × 10⁻⁴ | — | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone | |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Cavia porcellus | cortisonehomogenates of transiently transfected COS7 cells | — | 0.0082 | — | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone | |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Cavia porcellus | cortisone | 0.009 | 6 × 10⁻⁴ | 22 | pH 6, 37 °C | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Homo sapiens | cortisol | 0.185 | 0.0029 | 63 | pH 9.2, 37 °C | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisol |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Homo sapiens | cortisone | — | 0.0019 | — | pH 7.4, 37 °C | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Homo sapiens | cortisone1-3 h incubation with cortisone plus 3H-labeled tracer | — | 3.3 × 10⁻⁴ | — | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone | |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Homo sapiens | cortisonehomogenates of transiently transfected COS7 cells | — | 0.0089 | — | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone | |
| 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) | Homo sapiens | cortisone | 0.027 | 8 × 10⁻⁴ | 25 | pH 6, 37 °C | Open record: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), cortisone |