CatLogenzyme kinetics catalog

Values CatLog read from this paper

Functional role of dimerization of human peptidylarginine deiminase 4 (PAD4)

PMID 21731701doi:10.1371/journal.pone.0021314Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 18 records (36 values) from this paper: peptidylarginine deiminase 4 (PAD4) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 18 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 3.5.3.15

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
peptidylarginine deiminase 4 (PAD4)Homo sapiensN-alpha-benzoyl-L-arginine ethyl ester13.40.3143 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant D273A/R544AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester13.50.3539 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant D547AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester11.60.3632 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant D547EHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester8.90.7212 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant D547NHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester12.20.8614 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant E281AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester12.10.4527 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester12.20.4726 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8A/D547AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester10.70.427 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8EHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester7.31.066.9 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8E/D547EHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester3.32.771.2 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8HHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester13.30.4728 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8KHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester10.80.522 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8LHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester5.31.363.9 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant R8QHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester12.20.620 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant Y237AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester13.90.3639 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant Y237A/E281AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester13.20.3835 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant Y435AHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester5.92.332.5 calc.pH 7.5, 25 °COpen
peptidylarginine deiminase 4 (PAD4)variant Y435NHomo sapiensN-alpha-benzoyl-L-arginine ethyl ester42.731.5 calc.pH 7.5, 25 °COpen