Values CatLog read from this paper
Point mutations (Q19P and N23K) increase the operational solubility of a 2alpha-O-benzoyltransferase that conveys various acyl groups from CoA to a taxane acceptor
PMID 20108947doi:10.1021/np900524dOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 17 records (51 values) from this paper: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) from Taxus cuspidata.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | (E)-but-2-enoyl-CoA | 0.028 | 0.049 | 0.58 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, (E)-but-2-enoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 1,3-thiazole-5-carbonyl-CoA | 0.0022 | 0.37 | 0.0058 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 1,3-thiazole-5-carbonyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 2-fluorobenzoyl-CoA | 0.0108 | 0.17 | 0.065 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 2-fluorobenzoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 2-furoyl-CoA | 0.0018 | 0.12 | 0.0153 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 2-furoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 2-methylpropanoyl-CoA | 3.8 × 10⁻⁴ | 0.055 | 0.007 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 2-methylpropanoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 3-fluorobenzoyl-CoA | 0.00125 | 0.27 | 0.0047 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 3-fluorobenzoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 3-furoyl-CoA | 2.3 × 10⁻⁴ | 0.0064 | 0.037 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 3-furoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 4-chlorobenzoyl-CoA | 2.7 × 10⁻⁴ | 0.042 | 0.0063 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 4-chlorobenzoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 4-fluorobenzoyl-CoA | 0.00127 | 0.12 | 0.0103 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 4-fluorobenzoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | 4-methylbenzoyl-CoA | 3.5 × 10⁻⁴ | 0.012 | 0.03 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, 4-methylbenzoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | acetyl-CoA | 0.0042 | 0.51 | 0.0082 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, acetyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | benzoyl-CoA | 0.0032 | 0.11 | 0.03 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, benzoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | butanoyl-CoA | 0.02 | 0.057 | 0.35 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, butanoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | hexanoyl-CoA | 1.7 × 10⁻⁴ | 0.042 | 0.004 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, hexanoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | propanoyl-CoA | 0.0058 | 0.12 | 0.05 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, propanoyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | thiophene-2-carbonyl-CoA | 0.0022 | 0.045 | 0.048 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, thiophene-2-carbonyl-CoA |
| taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase)variant Q19P/N23K | Taxus cuspidata | thiophene-3-carbonyl-CoA | 0.0085 | 0.18 | 0.048 | pH 7.4, 31 °C | Open record: taxane 2α-O-benzoyltransferase (mTBT, 2-O-debenzoyltaxane 2-O-benzoyltransferase) variant Q19P/N23K, thiophene-3-carbonyl-CoA |